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The effect of ciprofloxacin and doxycycline plus metronidazole on lower genital tract flora in patients with proven pelvic inflammatory disease

The effect of ciprofloxacin and doxycycline plus metronidazole on lower genital tract flora in... Alterations in the lower genital tract flora were studied during antimicrobial treatment of 36 women with acute pelvic inflammatory disease (PID). Sixteen women received ciprofloxacin, and 20 received doxycycline plus metronidazole. Both regimes eradicatedChlamydia trachomatis in all cases andNeisseria gonorrhoeae in all except one in which combination treatment failed because of resistance of the organism to tetracycline. Both regimes eradicatedMycoplasma hominis in all cases, while ciprofloxacin was somewhat less effective than combination treatment againstUreaplasma urealyticum. Ciprofloxacin was less effective than combination treatment againstGardnerella vaginalis. The incidence ofCandida infection increased equally in both groups, although symptoms necessitating antifungal treatment were rare. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Gynecology and Obstetrics Springer Journals

The effect of ciprofloxacin and doxycycline plus metronidazole on lower genital tract flora in patients with proven pelvic inflammatory disease

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Publisher
Springer Journals
Copyright
Copyright © 1991 by Springer-Verlag
Subject
Medicine & Public Health; Gynecology; Obstetrics/Perinatology/Midwifery; Endocrinology; Human Genetics
ISSN
0932-0067
eISSN
1432-0711
DOI
10.1007/BF02390368
Publisher site
See Article on Publisher Site

Abstract

Alterations in the lower genital tract flora were studied during antimicrobial treatment of 36 women with acute pelvic inflammatory disease (PID). Sixteen women received ciprofloxacin, and 20 received doxycycline plus metronidazole. Both regimes eradicatedChlamydia trachomatis in all cases andNeisseria gonorrhoeae in all except one in which combination treatment failed because of resistance of the organism to tetracycline. Both regimes eradicatedMycoplasma hominis in all cases, while ciprofloxacin was somewhat less effective than combination treatment againstUreaplasma urealyticum. Ciprofloxacin was less effective than combination treatment againstGardnerella vaginalis. The incidence ofCandida infection increased equally in both groups, although symptoms necessitating antifungal treatment were rare.

Journal

Archives of Gynecology and ObstetricsSpringer Journals

Published: Mar 30, 2006

References