“Whoa! It's like Spotify but for academic articles.”

Instant Access to Thousands of Journals for just $40/month

Get 2 Weeks Free

Host factors are important in determining clinical outcomes of Helicobacter pylori infection



J Gastroenterol 2006; 41:1–9 DOI 10.1007/s00535-005-1743-4 Review Host factors are important in determining clinical outcomes of Helicobacter pylori infection Tsutomu Chiba1, Hiroshi Seno1, Hiroyuki Marusawa1, Yoshio Wakatsuki2, and Kazuichi Okazaki3 Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kawahara-cho 54, Shogoin, Sakyo, Kyoto 606-8507, Japan 2 Department of Geriatric Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan 3 Department of Gastroenterology, Kansai Medical University, Osaka, Japan Key words: H. pylori, gastritis, peptic ulcer, gastric cancer, MALT lymphoma Introduction Nearly half the population in Japan is infected with Helicobacter pylori, and consequently the prevalence of gastric cancer is very high. Not everyone with H. pylori infection develops gastric cancer, however. Indeed, the relationship between H. pylori infection and gastric cancer is quite different from that between hepatitis C virus infection and hepatocellular carcinoma. Uemura et al. reported that gastric cancer developed in approximately 3% of H. pylori-infected patients during a 7.8-year follow-up period,1 whereas the annual incidence of hepatocellular carcinoma in cirrhotic patients with hepatitis C virus infection was 2.0%–6.6%.2 Moreover, although the prevalence of H. pylori infection is similarly high in Asian countries, the incidence of gastric cancer in southern Asia is clearly lower



Journal of GastroenterologySpringer Journals

Published: Jan 1, 2006

DOI: 10.1007/s00535-005-1743-4

Free Preview of First Page

Loading next page...

You're reading a free preview. Subscribe to read the entire article.

And millions more from thousands of peer-reviewed journals, for just $40/month

Get 2 Weeks Free

To be the best researcher, you need access to the best research

  • With DeepDyve, you can stop worrying about how much articles cost, or if it's too much hassle to order — it's all at your fingertips. Your research is important and deserves the top content.
  • Read from thousands of the leading scholarly journals from Springer, Elsevier, Nature, IEEE, Wiley-Blackwell and more.
  • All the latest content is available, no embargo periods.

Stop missing out on the latest updates in your field

  • We’ll send you automatic email updates on the keywords and journals you tell us are most important to you.
  • There is a lot of content out there, so we help you sift through it and stay organized.