Responsive brain stimulation in epilepsy

Responsive brain stimulation in epilepsy Stimulation devices are considered in patients with drug-resistant epilepsy and who are not surgical candidates. Responsive neurostimulation (RNS) is a cortically based stimulator activated by electrocorticography (ECoG) patterns. Stimulation is applied directly to the seizure focus. The vagal nerve stimulator AspireSR 106 is also a responsive device which, in addition to basal stimulation, is activated by tachycardia. Deep brain stimulation of the anterior nucleus of the thalamus is used in Europe for intractable epilepsy and yields similar response rates to RNS using duty cycle stimulation. Chronic subthreshold cortical stimulation is an experimental form of constant, low-level stimulation applied to a seizure focus. These modalities are discussed and compared in this review. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Therapeutic Advances in Chronic Disease SAGE

Responsive brain stimulation in epilepsy

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Publisher
SAGE
Copyright
© The Author(s), 2018
ISSN
2040-6223
eISSN
2040-6231
D.O.I.
10.1177/2040622318774173
Publisher site
See Article on Publisher Site

Abstract

Stimulation devices are considered in patients with drug-resistant epilepsy and who are not surgical candidates. Responsive neurostimulation (RNS) is a cortically based stimulator activated by electrocorticography (ECoG) patterns. Stimulation is applied directly to the seizure focus. The vagal nerve stimulator AspireSR 106 is also a responsive device which, in addition to basal stimulation, is activated by tachycardia. Deep brain stimulation of the anterior nucleus of the thalamus is used in Europe for intractable epilepsy and yields similar response rates to RNS using duty cycle stimulation. Chronic subthreshold cortical stimulation is an experimental form of constant, low-level stimulation applied to a seizure focus. These modalities are discussed and compared in this review.

Journal

Therapeutic Advances in Chronic DiseaseSAGE

Published: Jul 1, 2018

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