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such as progression-free survival. Studies that have evaluated thalidomide or lenalidomide maintenance therapy have demonstrated an overall survival (OS) benefit in individuals with multiple myeloma who received high ...
to consider. In this broad scoping review of available therapies in relapsed/refractory multiple myeloma (RRMM), we cover the pharmacologic mechanisms underlying active therapies such as immunomodulatory agents ...
. Anticoagulant prophylaxis for thromboembolic adverse events was important (26). Thalidomide maintenance therapy after ASCT Thalidomide maintenance therapy has the potential to modulate residual multiple myeloma ...
Abstract Purpose The pharmacology , pharmacokinetics, clinical efficacy, safety, dosage and administration, and place in therapy of pomalidomide for the management of refractory multiple myeloma ...
in reducing serum calcium as the same dose given over 5 days without inducing adverse effects. In two pilot studies in multiple myeloma patients the progression of skeletal destruction and the incidence of new ...
]. Bortezomib The combination of bortezomib with MP (VMP) was explored in the large phase III Velcade as Initial Standard Therapy in Multiple Myeloma : Assessment with Melphalan and Prednisone (VISTA) trial ...
Search ADS PubMed WorldCat Mariz JM , Esteves GV. Review of therapy for relapsed/refractory multiple myeloma : focus on lenalidomide . Curr Opin Oncol 2012 ; 24 ( Suppl. 2 ): S3 – 11 . Google Scholar PubMed ...
was approved in the European Union, in combination with pomalidomide and dexamethasone, for the treatment of patients with multiple myeloma who have already received therapy but whose disease did not respond ...
Abstract Purpose The pharmacology , clinical efficacy, safety, cost, dosage and administration, and place in therapy of carfilzomib for the treatment of multiple myeloma (MM) are reviewed . Summary ...
Abstract Objectives Carfilzomib is a new agent for the treatment of relapsed and refractory multiple myeloma (MM). This article presents a comprehensive overview of the pharmacokinetics ...
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