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THERAPY for Leukapheresis : Technique Granulocyte Transfusion Edmund J. Samuel K. M. M.D. M.D., M.D., Moser, Doering, Morgan, Anthony THE NUMBER of in ten units Case neutrophils Report of coat ...
Techniques for collecting granulocytes for transfusion either to neutropenic patients or to neonates are described. Currently, the best granulocyte concentrates are prepared using continuous‐flow ...
. Granulocytes obtained by gravity leukapheresis were normal morphologically and had normal bactericidal capacity. Serial determinations showed no changes before and after donation of coagulation profile and serum ...
Granulocyte transfusion therapy has become relatively routine in centers treating patients with hematologic malignancies. The yield of granulocytes has been improved with newer leukapheresis ...
Filtration leukapheresis (FL) is an effective and economic technique to collect large amounts of neutrophils for substitutional treatment of severe, transient neutropenia. An essential factor ...
separate units containing suiselent numbers o cells for transfusion can he f obtdned from p h e d s of one donor. insure efficient granulocyte collection when discontinuous-flow centrifugation leukapheresis ...
to transfusion . There was no difference in mortality between patients treated with cells collected by filtration (FL) or intermittent flow centrifugation (IFCL) leukapheresis techniques . Transfusion reactions were ...
leukapheresis techniques are available. However, both corticosteroids and hydroxyethyl starch are required for optimal granulocyte collection. In this paper, we critically compare the three major cell separators ...
. This perceived lack of efficacy has been attributed primarily to the fact that the dose of granulocytes obtainable with standard leukapheresis techniques has been inadequate. With the availability of recombinant ...
by normal donors undergoing three methods of pheresis used for the preparation of platelets and/or granulocytes for transfusion . Filtration leukapheresis was associated with a mean loss per donation of 1.7 ...
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