Extramedullary Hematopoiesis Presenting as Bilateral Glomus Tympanicum—First Case Report in a Pediatric Patient and With Bilateral Presentation

Extramedullary Hematopoiesis Presenting as Bilateral Glomus Tympanicum—First Case Report in a... To the best of our knowledge, this is the first case report of middle ear extramedullary hematopoiesis (EMH) in a pediatric patient as well as the first bilateral presentation reported in both children and adults. We report a 13-year-old African-American female with sickle cell disease who developed bilateral hearing loss, with magnetic resonance imaging findings consistent with bilateral glomus tympanicum (GT). Upon excisional biopsy, however, EMH was diagnosed histologically. Besides its novelty, this case highlights the importance of considering EMH in the differential diagnosis of GT including cases with bilateral presentation that may be otherwise highly suggestive of the familial form of GT. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric and Developmental Pathology SAGE

Extramedullary Hematopoiesis Presenting as Bilateral Glomus Tympanicum—First Case Report in a Pediatric Patient and With Bilateral Presentation

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Publisher
SAGE Publications
Copyright
© 2017, Society for Pediatric Pathology All rights reserved
ISSN
1093-5266
eISSN
1615-5742
D.O.I.
10.1177/1093526617704267
Publisher site
See Article on Publisher Site

Abstract

To the best of our knowledge, this is the first case report of middle ear extramedullary hematopoiesis (EMH) in a pediatric patient as well as the first bilateral presentation reported in both children and adults. We report a 13-year-old African-American female with sickle cell disease who developed bilateral hearing loss, with magnetic resonance imaging findings consistent with bilateral glomus tympanicum (GT). Upon excisional biopsy, however, EMH was diagnosed histologically. Besides its novelty, this case highlights the importance of considering EMH in the differential diagnosis of GT including cases with bilateral presentation that may be otherwise highly suggestive of the familial form of GT.

Journal

Pediatric and Developmental PathologySAGE

Published: May 1, 2018

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