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Drug Interactions Involving the Drugs of Abuse

Drug Interactions Involving the Drugs of Abuse Drug Interactions Involving the Drugs of Abuse by John M. Davis, Joseph Sekerke and David S. Janowsky systems which control drug metabolism in the liver. In Introduction most situations in which liver enzymes are activated, THIS REVIEW DESCRIBES DRUG INTERACTIONS whic h may reduction of pharmacologie and toxic effects occurs. How- occur in situations involving drugs of abuse. These ever, in some situations certain compounds can inhibit interactions may consist of drug interactions between two the metabolism of other compounds, thus resulting in an different drugs of abuse or a drug interaction between a increased plasma level and an increased pharmacologie drug of abuse and another drug. The pharmacology, clin- effect. Also, certain drugs can affect the renal excretion ical effects, side effects and toxicology of the individual of other drugs. We will illustrate the above various drugs of abuse will be reviewed in separate monographs. types of drug interactions involving drugs of abuse in This review specifically will describe how one drug will the following paragraphs. interact with another drug in producing a new effect, not One drug can influence another drug's absorption identical to the effects of the individual drugs alone. into the body by altering pH http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Drug Intelligence & Clinical Pharmacy SAGE

Drug Interactions Involving the Drugs of Abuse

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References (147)

Publisher
SAGE
Copyright
© 1974 SAGE Publications
ISSN
0012-6578
DOI
10.1177/106002807400800304
Publisher site
See Article on Publisher Site

Abstract

Drug Interactions Involving the Drugs of Abuse by John M. Davis, Joseph Sekerke and David S. Janowsky systems which control drug metabolism in the liver. In Introduction most situations in which liver enzymes are activated, THIS REVIEW DESCRIBES DRUG INTERACTIONS whic h may reduction of pharmacologie and toxic effects occurs. How- occur in situations involving drugs of abuse. These ever, in some situations certain compounds can inhibit interactions may consist of drug interactions between two the metabolism of other compounds, thus resulting in an different drugs of abuse or a drug interaction between a increased plasma level and an increased pharmacologie drug of abuse and another drug. The pharmacology, clin- effect. Also, certain drugs can affect the renal excretion ical effects, side effects and toxicology of the individual of other drugs. We will illustrate the above various drugs of abuse will be reviewed in separate monographs. types of drug interactions involving drugs of abuse in This review specifically will describe how one drug will the following paragraphs. interact with another drug in producing a new effect, not One drug can influence another drug's absorption identical to the effects of the individual drugs alone. into the body by altering pH

Journal

Drug Intelligence & Clinical PharmacySAGE

Published: Mar 1, 1974

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