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Abstract Objectives To investigate the effects of endotheline -1 (ET-1) receptor antagonism and/or chronic blockade of nitric oxide (NO) production on pregnancy outcome in the rat. Methods Pregnant ...
of the L-NAME-induced, preeclampsia-like syndrome during pregnancy, although at later stages other mechanisms may come into play. Chronic Blockade of Nitric Oxide - Synthase and Endothelin Receptors During ...
Objective: To investigate the effects of chronic blockade of nitric oxide (NO) production and endothelin (ET-1) receptor antagonism on edothelial and vascular smooth muscle function of the uterine ...
Abstract Objective To investigate the effects of chronic blockade of nitric oxide (NO) production and endothelin (ET-1) receptor antagonism on edothelial and vascular smooth muscle function ...
1. Chronic inhibition of nitric oxide synthase (NOS) results in a persistent hypertension, while chronic blockade of endothelin ETA receptors has little effect on arterial pressure. These findings ...
Abstract Endothelium-derived nitric oxide (NO) and endothelin (ET)-1 interact to regulate vascular tone. In congestive heart failure (CHF), the release and/or the activity of both factors is affected ...
in mesenteric, arteries of DOCA-salt rats. Inhibition of nitric oxide synthase activity did not restore contraction to ET-1 in coronary small arteries. However contractions to ET-1 were enhanced in mesenteric ...
hypercholesterolaemia HR heart rate LAP left atrial pressure l ‐NAME N G ‐nitro‐ l ‐arginine methyl ester LDL low‐density lipoprotein MAP mean arterial pressure NO nitric oxide NOS nitric oxide synthase PAP pulmonary ...
by inhibition of nitric oxide synthesis and by endothelin -B receptor blockade , Circulation , 1998 , vol. 97 (pg. 752 - 756 ) Google Scholar Crossref Search ADS PubMed WorldCat [27] Halcox J.P.J. , Sharma ...
vasodilation and hyperfiltration during chronic nitric oxide synthase blockade in conscious pregnant rats . Circ Res 1996 ; 79 : 1161 – 1166 . Google Scholar Crossref Search ADS PubMed WorldCat 41. Bobadilla RA ...
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