Inside back cover

Inside back cover Showcasing research from Professor Chun-yang Zhang’s As featured in: laboratory, College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan, China. Controllable fabrication of bio-bar codes for dendritically amplifi ed sensing of human T-lymphotropic viruses We demonstrate for the fi rst time the controllable fabrication of bio-bar codes for dendritically amplifi ed sensing of low-abundant HTLV-II DNA by the integration of terminal deoxynucleotidyl transferase-catalyzed template-free polymerization extension with bio-bar-code amplifi cation. This method exhibits ultrahigh sensitivity with a limit of detection of as low as 0.50 aM and a large dynamic range of 9 orders of magnitude from 1 aM to 1 nM, and it can be applied for the discrimination of a single-base See Chun-yang Zhang et al., Chem. Sci., 2018, 9, 4942. mismatch and the measurement of HTLV-II DNA in both human serum and human T-lymphocytic leukemia cells. rsc.li/chemical-science Registered charity number: 207890 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chemical Science Royal Society of Chemistry

Inside back cover

Chemical Science , Volume 9 (22): 1 – Jun 6, 2018
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Publisher
The Royal Society of Chemistry
Copyright
This journal is © The Royal Society of Chemistry
ISSN
2041-6520
D.O.I.
10.1039/C8SC90118J
Publisher site
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Abstract

Showcasing research from Professor Chun-yang Zhang’s As featured in: laboratory, College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan, China. Controllable fabrication of bio-bar codes for dendritically amplifi ed sensing of human T-lymphotropic viruses We demonstrate for the fi rst time the controllable fabrication of bio-bar codes for dendritically amplifi ed sensing of low-abundant HTLV-II DNA by the integration of terminal deoxynucleotidyl transferase-catalyzed template-free polymerization extension with bio-bar-code amplifi cation. This method exhibits ultrahigh sensitivity with a limit of detection of as low as 0.50 aM and a large dynamic range of 9 orders of magnitude from 1 aM to 1 nM, and it can be applied for the discrimination of a single-base See Chun-yang Zhang et al., Chem. Sci., 2018, 9, 4942. mismatch and the measurement of HTLV-II DNA in both human serum and human T-lymphocytic leukemia cells. rsc.li/chemical-science Registered charity number: 207890

Journal

Chemical ScienceRoyal Society of Chemistry

Published: Jun 6, 2018

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