A synthetic nanoreceptor, cucurbituril (CB), fully encapsulated pentylenetetrazol (PTZ), a seizure-inducing model drug. As a consequence of the encapsulation, the development of PTZ induced convulsion behaviors in both larval zebrafish and mouse models were dramatically alleviated, suggesting that CB holds great neuroprotection potential against neurotoxic drugs for clinical applications.
Nanoscale – Royal Society of Chemistry
Published: May 2, 2018
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