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THE EFFECT OF SOME OF THE CHEMICAL CONSTITUENTS OF TUBERCLE BACILLI ON THE PROTOPLASM OF AMOEBA DUBIA

THE EFFECT OF SOME OF THE CHEMICAL CONSTITUENTS OF TUBERCLE BACILLI ON THE PROTOPLASM OF AMOEBA... 1. Protein fractions derived from tubercle bacilli are toxic to the interior of Amœba dubia but have no action on the plasmalemma. 2. Phosphatide fractions dissolve the plasmalemma but have no effect on the internal cytoplasm. 3. The fatty acid fraction has a marked solvent action on the plasmalemma when brought in contact with the surface of the cell. When injected it may slowly penetrate the cytoplasm to dissolve the contiguous plasmalemma. 4. The polysaccharide fraction has no effect upon the surface membrane or upon the internal cytoplasm of Amœba dubia . Footnotes Submitted: 9 May 1928 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Experimental Medicine Rockefeller University Press

THE EFFECT OF SOME OF THE CHEMICAL CONSTITUENTS OF TUBERCLE BACILLI ON THE PROTOPLASM OF AMOEBA DUBIA

The Journal of Experimental Medicine , Volume 48 (2): 193 – Aug 1, 1928

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References (6)

Publisher
Rockefeller University Press
Copyright
© 1928 Rockefeller University Press
ISSN
0022-1007
eISSN
1540-9538
DOI
10.1084/jem.48.2.193
Publisher site
See Article on Publisher Site

Abstract

1. Protein fractions derived from tubercle bacilli are toxic to the interior of Amœba dubia but have no action on the plasmalemma. 2. Phosphatide fractions dissolve the plasmalemma but have no effect on the internal cytoplasm. 3. The fatty acid fraction has a marked solvent action on the plasmalemma when brought in contact with the surface of the cell. When injected it may slowly penetrate the cytoplasm to dissolve the contiguous plasmalemma. 4. The polysaccharide fraction has no effect upon the surface membrane or upon the internal cytoplasm of Amœba dubia . Footnotes Submitted: 9 May 1928

Journal

The Journal of Experimental MedicineRockefeller University Press

Published: Aug 1, 1928

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