SATELLITE CELL OF SKELETAL MUSCLE FIBERS

SATELLITE CELL OF SKELETAL MUSCLE FIBERS B R I E r N O • ~ S merely d o r m a n t myoblasts that failed to fuse with other myoblasts and are ready to recapitulate the embryonic development of skeletal muscle fiber when the main multinucleate cell is damaged. O f course, t h a t b o t h mechanisms m i g h t be operating simultaneously as the source of the "free" cells is, indeed, a further possibility since one mechanism need not preclude the other. A third possibility is that the satellite cells are " w a n d e r i n g " cells that have penetrated the basem e n t m e m b r a n e and are lying u n d e r n e a t h it ready to be mobilized into activity u n d e r the proper conditions. T h e correct explanation of the origin and role of the satellite cells must await the outcome of further studies3 1 A thorough search of both Dr. Palade's and Dr. Moore's collection of electron micrographs of cardiac muscle have not revealed either peripheral nuclei or satellite cells. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Cell Biology Rockefeller University Press

SATELLITE CELL OF SKELETAL MUSCLE FIBERS

The Journal of Cell Biology, Volume 9 (2): 493 – Feb 1, 1961

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Publisher
Rockefeller University Press
Copyright
Copyright © 1961 by The Rockefeller University Press
ISSN
0021-9525
eISSN
1540-8140
DOI
10.1083/jcb.9.2.493
Publisher site
See Article on Publisher Site

Abstract

B R I E r N O • ~ S merely d o r m a n t myoblasts that failed to fuse with other myoblasts and are ready to recapitulate the embryonic development of skeletal muscle fiber when the main multinucleate cell is damaged. O f course, t h a t b o t h mechanisms m i g h t be operating simultaneously as the source of the "free" cells is, indeed, a further possibility since one mechanism need not preclude the other. A third possibility is that the satellite cells are " w a n d e r i n g " cells that have penetrated the basem e n t m e m b r a n e and are lying u n d e r n e a t h it ready to be mobilized into activity u n d e r the proper conditions. T h e correct explanation of the origin and role of the satellite cells must await the outcome of further studies3 1 A thorough search of both Dr. Palade's and Dr. Moore's collection of electron micrographs of cardiac muscle have not revealed either peripheral nuclei or satellite cells.

Journal

The Journal of Cell BiologyRockefeller University Press

Published: Feb 1, 1961

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