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GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS

GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS Experimental infectious mouse hepatitis is associated with an increase in glutamic-oxaloacetic transaminase activity of the serum (SGO-T). A relationship appears to exist between the rise in SGO-T activity and ( a ) the size of the virus inoculum, ( b ) the blood virus titer, and ( c ) the degree of liver necrosis. Trauma to the liver following partial hepatectomy results in a rise in SGO-T activity in mice. Although mouse hepatitis differs from human hepatitis in the incubation period, histological changes, and natural course, both infections bring about comparable changes in SGO-T activity. Footnotes Submitted: 17 August 1955 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Experimental Medicine Rockefeller University Press

GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS

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References (4)

Publisher
Rockefeller University Press
Copyright
© 1955 Rockefeller University Press
ISSN
0022-1007
eISSN
1540-9538
DOI
10.1084/jem.102.6.699
Publisher site
See Article on Publisher Site

Abstract

Experimental infectious mouse hepatitis is associated with an increase in glutamic-oxaloacetic transaminase activity of the serum (SGO-T). A relationship appears to exist between the rise in SGO-T activity and ( a ) the size of the virus inoculum, ( b ) the blood virus titer, and ( c ) the degree of liver necrosis. Trauma to the liver following partial hepatectomy results in a rise in SGO-T activity in mice. Although mouse hepatitis differs from human hepatitis in the incubation period, histological changes, and natural course, both infections bring about comparable changes in SGO-T activity. Footnotes Submitted: 17 August 1955

Journal

The Journal of Experimental MedicineRockefeller University Press

Published: Dec 1, 1955

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