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S. Rieder (1955)
Biochemical PreparationsThe Yale Journal of Biology and Medicine, 28
(1956)
J. Exp. ivied
The bactericidal substance present in mitochondrial extracts from rat leucocytes was found to be non-dialyzable, fractionated at 30 per cent (NH 4 SO 4 saturation and was able to withstand temperatures up to 100°C. The tentative identification of a lipoprotein as the responsible bactericidal substance is based on various observations; an ultraviolet absorption at a peak associated with alpha, beta unsaturated fatty acids, 205 to 208 mµ, inactivation of the bactericidal substance by ether treatment at –70°C. but not at 0°C. and inhibition of the bactericidal activity with lipase treatment as well as with trypsin. Footnotes Submitted: 27 January 1957
The Journal of Experimental Medicine – Rockefeller University Press
Published: Jun 1, 1957
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