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A GROWTH INHIBITORY SUBSTANCE FOR THE INFLUENZA GROUP OF ORGANISMS IN THE BLOOD OF VARIOUS ANIMAL SPECIES

A GROWTH INHIBITORY SUBSTANCE FOR THE INFLUENZA GROUP OF ORGANISMS IN THE BLOOD OF VARIOUS ANIMAL... 1. 5 per cent sheep blood agar is a selective medium for beta hemolytic streptococci in throat cultures since sheep blood inhibits the growth of bacillus X ( H. hemolyticus ) and B. parainfluenzae hemolyticus . The growth of H. influenzae is also inhibited by sheep blood. 2. The inhibitory action of sheep blood resides in the erythrocytes and is thermolabile. Disruption of the cell by laking has no effect upon the inhibitor. 3. The bloods of animals closely related to the sheep, such as the goat and the cow, have a similar inhibitory action on the growth of hemolytic and non-hemolytic members of the influenza group, while human blood contains a similar but less powerful inhibitor for these organisms. 4. Members of the influenza group grow well on unheated rodent blood: rabbit, guinea pig, and rat. 5. These organisms also grow fairly well on unheated horse blood. Footnotes Submitted: 7 December 1937 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Experimental Medicine Rockefeller University Press

A GROWTH INHIBITORY SUBSTANCE FOR THE INFLUENZA GROUP OF ORGANISMS IN THE BLOOD OF VARIOUS ANIMAL SPECIES

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References (4)

Publisher
Rockefeller University Press
Copyright
© 1938 Rockefeller University Press
ISSN
0022-1007
eISSN
1540-9538
DOI
10.1084/jem.67.3.429
Publisher site
See Article on Publisher Site

Abstract

1. 5 per cent sheep blood agar is a selective medium for beta hemolytic streptococci in throat cultures since sheep blood inhibits the growth of bacillus X ( H. hemolyticus ) and B. parainfluenzae hemolyticus . The growth of H. influenzae is also inhibited by sheep blood. 2. The inhibitory action of sheep blood resides in the erythrocytes and is thermolabile. Disruption of the cell by laking has no effect upon the inhibitor. 3. The bloods of animals closely related to the sheep, such as the goat and the cow, have a similar inhibitory action on the growth of hemolytic and non-hemolytic members of the influenza group, while human blood contains a similar but less powerful inhibitor for these organisms. 4. Members of the influenza group grow well on unheated rodent blood: rabbit, guinea pig, and rat. 5. These organisms also grow fairly well on unheated horse blood. Footnotes Submitted: 7 December 1937

Journal

The Journal of Experimental Medicine – Rockefeller University Press

Published: Mar 1, 1938

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