Transcription-independent Induction of ERBB1 through Hypoxia-inducible Factor 2A Provides Cardioprotection during Ischemia and Reperfusion.

Transcription-independent Induction of ERBB1 through Hypoxia-inducible Factor 2A Provides... Hypoxia-inducible factors are stabilized and provide protection from ischemia and reperfusion injury in the setting of myocardial ischemia.In the setting of ischemia, myocyte-specific hypoxia-inducible factor 2A induces expression of amphiregulin, which is an epidermal growth factor that binds to epidermal growth factor receptor 1 (ERBB1) in the myocardium. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Anesthesiology Pubmed

Transcription-independent Induction of ERBB1 through Hypoxia-inducible Factor 2A Provides Cardioprotection during Ischemia and Reperfusion.

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Transcription-independent Induction of ERBB1 through Hypoxia-inducible Factor 2A Provides Cardioprotection during Ischemia and Reperfusion.

Anesthesiology: 1 – Dec 7, 2019

Abstract

Hypoxia-inducible factors are stabilized and provide protection from ischemia and reperfusion injury in the setting of myocardial ischemia.In the setting of ischemia, myocyte-specific hypoxia-inducible factor 2A induces expression of amphiregulin, which is an epidermal growth factor that binds to epidermal growth factor receptor 1 (ERBB1) in the myocardium.
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DOI
10.1097/ALN.0000000000003037

Abstract

Hypoxia-inducible factors are stabilized and provide protection from ischemia and reperfusion injury in the setting of myocardial ischemia.In the setting of ischemia, myocyte-specific hypoxia-inducible factor 2A induces expression of amphiregulin, which is an epidermal growth factor that binds to epidermal growth factor receptor 1 (ERBB1) in the myocardium.

Journal

AnesthesiologyPubmed

Published: Dec 7, 2019

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