Launching APOLLO: The Role of APOL1 Genetic Variants in Live- and Deceased-Donor Kidney Transplantation

Launching APOLLO: The Role of APOL1 Genetic Variants in Live- and Deceased-Donor Kidney... COMMENTARY meta-analysis of 4 hypertension Launching APOLLO: trials, subjects with 1 or 2 APOL1 The Role of APOL1 Genetic risk alleles and mild to moderate hypertension had a greater fall in Variants in Live- and Deceased-Donor systolic blood pressure with can- desartan (12 vs. 8 mg Hg) and a Kidney Transplantation greater decline in albuminuria (8 1 1 vs. 4 mg/d), compared with those Federico Fuentes and Jeffrey B. Kopp with zero APOL1 risk alleles, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Dis- whereas there were no differences eases, National Institutes of Health, Bethesda, Maryland, USA by genotype for thiazides or beta blockers. Candesartan is a high- Kidney Int Rep (2020) 5, 252–254; https://doi.org/10.1016/j.ekir.2019.12.014 potency angiotensin receptor Published by Elsevier Inc. on behalf of the International Society of Nephrology. This is blocker with a long duration of an open access article under the CC BY-NC-ND license (http://creativecommons.org/ action. It is more effective at blood licenses/by-nc-nd/4.0/). pressure lowering than losartan and comparable to telmisartan and See Clinical Research on Page 278 S1 valsartan. Whether the effect observed in APOL1 risk allele nthis issue of Kidney Interna- To date, there has not been a carriers is a http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Kidney International Reports Pubmed Central

Launching APOLLO: The Role of APOL1 Genetic Variants in Live- and Deceased-Donor Kidney Transplantation

Kidney International Reports, Volume 5 (3) – Dec 27, 2019
Preview Only
3 pages

Loading next page...
 
/lp/pubmed-central/launching-apollo-the-role-of-apol1-genetic-variants-in-live-and-L2oywW0eSi
Publisher
Pubmed Central
eISSN
2468-0249
DOI
10.1016/j.ekir.2019.12.014
Publisher site
See Article on Publisher Site

Abstract

COMMENTARY meta-analysis of 4 hypertension Launching APOLLO: trials, subjects with 1 or 2 APOL1 The Role of APOL1 Genetic risk alleles and mild to moderate hypertension had a greater fall in Variants in Live- and Deceased-Donor systolic blood pressure with can- desartan (12 vs. 8 mg Hg) and a Kidney Transplantation greater decline in albuminuria (8 1 1 vs. 4 mg/d), compared with those Federico Fuentes and Jeffrey B. Kopp with zero APOL1 risk alleles, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Dis- whereas there were no differences eases, National Institutes of Health, Bethesda, Maryland, USA by genotype for thiazides or beta blockers. Candesartan is a high- Kidney Int Rep (2020) 5, 252–254; https://doi.org/10.1016/j.ekir.2019.12.014 potency angiotensin receptor Published by Elsevier Inc. on behalf of the International Society of Nephrology. This is blocker with a long duration of an open access article under the CC BY-NC-ND license (http://creativecommons.org/ action. It is more effective at blood licenses/by-nc-nd/4.0/). pressure lowering than losartan and comparable to telmisartan and See Clinical Research on Page 278 S1 valsartan. Whether the effect observed in APOL1 risk allele nthis issue of Kidney Interna- To date, there has not been a carriers is a

Journal

Kidney International ReportsPubmed Central

Published: Dec 27, 2019

There are no references for this article.

Sorry, we don’t have permission to share this article on DeepDyve,
but here are related articles that you can start reading right now:

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off