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demonstrating that aversive associative olfactory learning in Drosophila is also dependent on octopamine signalling. Specifically, we used Drosophila Tβh (tyramine‐β‐hydroxylase) mutants , which lack octopamine ...
. 1999, Vol. 113, No. 2, 358-367 0735-7044/99/S3.00 Olfactory Associative Learning in Caenorhabditis elegans Is Impaired in lrn-1 and lrn-2 Mutants Glenn E. Morrison, Joseph Y. M. Wen, Susan Runciman ...
behavior in C. elegans. glr-1 mutants are deficient in an olfactory associative learning task, in which diacetyl (DA) is paired with acetic acid solution. glr-1 mutant nematodes are also impaired ...
found that chico mutations impair memory- associated synaptic plasticity in the mushroom bodies (MBs), neural centers for olfactory learning . Mutations in chico reduce expression of the rutabaga-type ...
by the primary olfactory neurons to higher processing centres. In contrast, expression of Rim-RNAi in the mushroom bodies (MBs), the main memory centre in flies, spared learning and memory suggesting ...
. Using both olfactory and visual learning assays, we found that associative learning is impaired in psn mutants compared with controls. Both the learning and synaptic defects could be rescued by expression ...
used to dissect the molecular mechanisms and circuits that underlie learning . Flies exhibit robust appetitive and aversive learning via training to associate odours with positive or negative stimuli ...
of NMJs showed no morphological or developmental differences between wild-type and wstd1 but TPI mutants exhibited learning impairments as assessed by olfactory associative learning assays.DiscussionOur ...
Training and temperature protocols are shown at the top of each panel. A: In contrast to wild type larvae, aversive olfactory learning and/or memory is impaired in rsh1 mutants tested 0 and 60 minutes after ...
is modulated by stimulus intensity [2], we find that although still impaired relative to their siblings, hip14 mutant animals are capable of habituation learning under conditions of reduced stimulus intensity ...
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