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Letters to the Editor / European Journal of Cardio-thoracic Surgery 28 (2005) 358–367 363 introduced (i.e. one more body) a simulation is necessary to Letter to the Editor verify Newton’s law of gravitation. In cardiac mechanics, there are many corruptors or complexities—e.g. heterogeneous tissue properties, hetero- a, b b John C. Criscione , Filiberto Rodriguez , D. Craig Miller geneous activation, anisotropic behavior, mechano-electric Department of Biomedical Engineering, feedback, variable preload, variable afterload and variable Texas A&M University, MS: 3120, heart rate. This list is larger; and so, like the gravitational College Station, TX 77843-3120, USA three-body problem, a simulation or model is necessary to Department of Cardiothoracic Surgery, verify the mechanics of our hypotheses on heart development, Stanford University, Stanford, CA, USA growth and remodeling, filling, synergy and timing of Received 21 March 2005; accepted 22 April 2005; Available online 4 June 2005 contraction, twisting, etcetera. As our knowledge of cell growth, fiber structure, and electrical propagation improve, Keywords: Cardiac Anatomy; Cardiac Microstructure; Cardiac Mechanics; Computer Modeling; Continuum Mechanics our models will become better representative and more enlightening. In our opinion, the most useful approach to defining We read with great interest the three recent review cardiac structure
European Journal of Cardio-Thoracic Surgery – Oxford University Press
Published: Aug 1, 2005
Keywords: Keywords Cardiac Anatomy Cardiac Microstructure Cardiac Mechanics Computer Modeling Continuum Mechanics
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