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The Effect of Weight History on Glucose and Lipids

The Effect of Weight History on Glucose and Lipids Few studies have examined the impact of weight history. Extant data from the Atherosclerosis Risk in Communities Study were used to compare risk factors for normal-weight (body mass index: 18.5–24.9 kg/m2) adults with a history of weight loss (n = 775) with those for persons with a history of weight maintenance (n = 5,164). In this 1987–1998 US study, the authors also compared risk factors for preobese (body mass index: 25.0–29.9 kg/m2) adults with a history of weight gain (n = 1,296) versus weight maintenance (n = 6,721). They used mixed-models regression to adjust for ethnicity, gender, age, education, field center, smoking, alcohol consumption, follow-up time, and follow-up body mass index. Compared with adults with a history of weight maintenance, adults with a 3-year history of weight loss had more favorable total and low density lipoprotein cholesterol levels and similar glucose, high density lipoprotein cholesterol, and triglyceride levels. In contrast, preobese adults with a 3-year history of weight gain had equivalent glucose and lipid levels at follow-up compared with adults with a history of weight maintenance. These findings suggest that, in addition to current weight, weight history may impact glucose and lipid levels. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Epidemiology Oxford University Press

The Effect of Weight History on Glucose and Lipids

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References (49)

Publisher
Oxford University Press
Copyright
American Journal of Epidemiology Copyright © 2005 by the Johns Hopkins Bloomberg School of Public Health All rights reserved
ISSN
0002-9262
eISSN
1476-6256
DOI
10.1093/aje/kwi151
pmid
15937022
Publisher site
See Article on Publisher Site

Abstract

Few studies have examined the impact of weight history. Extant data from the Atherosclerosis Risk in Communities Study were used to compare risk factors for normal-weight (body mass index: 18.5–24.9 kg/m2) adults with a history of weight loss (n = 775) with those for persons with a history of weight maintenance (n = 5,164). In this 1987–1998 US study, the authors also compared risk factors for preobese (body mass index: 25.0–29.9 kg/m2) adults with a history of weight gain (n = 1,296) versus weight maintenance (n = 6,721). They used mixed-models regression to adjust for ethnicity, gender, age, education, field center, smoking, alcohol consumption, follow-up time, and follow-up body mass index. Compared with adults with a history of weight maintenance, adults with a 3-year history of weight loss had more favorable total and low density lipoprotein cholesterol levels and similar glucose, high density lipoprotein cholesterol, and triglyceride levels. In contrast, preobese adults with a 3-year history of weight gain had equivalent glucose and lipid levels at follow-up compared with adults with a history of weight maintenance. These findings suggest that, in addition to current weight, weight history may impact glucose and lipid levels.

Journal

American Journal of EpidemiologyOxford University Press

Published: Jun 15, 2005

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