Social and biological pathways linking early life and adult disease

Social and biological pathways linking early life and adult disease Evidence is presented for a pathways model linking early life factors and adult disease, which takes account of the inter-relationships between social and biological risks throughout the lifecourse. Few studies, if any, have yet recorded adequate birth to death information which could be used to quantify the effects of different factors and their timing. Hence, there is only limited understanding of the extent to which biological and social risks experienced at different life stages combine to influence adult disease. However, some of the pathways between early and later life are suggested when evidence from earlier stages of the lifecourse is linked to that from studies at older ages, in which adult disease risk factors have been established. Further support for pathway effects is provided by studies showing that health outcomes of early biological insults can depend on the subsequent social and biological environment. Thus, it is argued that adult disease will be more fully understood when account is taken of the combined effects of social and biological risk occurring at different life stages. © The British Council « Previous | Next Article » Table of Contents This Article Br Med Bull (1997) 53 (1): 210-221. » Abstract Free Full Text (PDF) Free Classifications Article Services Article metrics Alert me when cited Alert me if corrected Find similar articles Similar articles in Web of Science Similar articles in PubMed Add to my archive Download citation Request Permissions Disclaimer Citing Articles Load citing article information Citing articles via CrossRef Citing articles via Scopus Citing articles via Web of Science Citing articles via Google Scholar Google Scholar Articles by Power, C. Articles by Hertzman, C. Search for related content PubMed PubMed citation Articles by Power, C. Articles by Hertzman, C. Related Content Load related web page information Share Email this article CiteULike Delicious Facebook Google+ Mendeley Twitter What's this? Search this journal: Advanced » Current Issue September 2015 115 (1) Alert me to new issues The Journal About this journal Rights & Permissions Dispatch date of the next issue We are mobile – find out more Journals Career Network Impact factor: 3.658 5-Yr impact factor: 4.420 Editor-in-Chief Dr Norman J Vetter View full editorial board Alerting Services Email table of contents Email Advance Access CiteTrack XML RSS feed Corporate Services Reprints Supplements For Authors Open access options for authors - visit Oxford Open Self-archiving policy Instructions to authors This journal enables compliance with the NIH Public Access Policys Policy var taxonomies = ("MED00010"); Most Most Read Hazards of heavy metal contamination Health hazards and waste management Noise pollution: non-auditory effects on health Environmental pollution and the global burden of disease Contaminants in drinking water: Environmental pollution and health » View all Most Read articles Most Cited The thrifty phenotype hypothesis: Type 2 diabetes INTERHEMISPHERIC DIFFERENCES IN THE LOCALIZATION OF PSYCHOLOGICAL PROCESSES IN MAN DEVELOPMENTAL CYCLES AND BIOLOGY OF PATHOGENIC TRYPANOSOMES METHODS FOR THE INVESTIGATION OF PERIPHERAL BLOOD FLOW Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease » View all Most Cited articles Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department. Online ISSN 1471-8391 - Print ISSN 0007-1420 Copyright © 2015 Oxford University Press Oxford Journals Oxford University Press Site Map Privacy Policy Cookie Policy Legal Notices Frequently Asked Questions Other Oxford University Press sites: Oxford University Press Oxford Journals China Oxford Journals Japan Academic & Professional books Children's & Schools Books Dictionaries & Reference Dictionary of National Biography Digital Reference English Language Teaching Higher Education Textbooks International Education Unit Law Medicine Music Online Products & Publishing Oxford Bibliographies Online Oxford Dictionaries Online Oxford English Dictionary Oxford Language Dictionaries Online Oxford Scholarship Online Reference Rights and Permissions Resources for Retailers & Wholesalers Resources for the Healthcare Industry Very Short Introductions World's Classics function fnc_onDomLoaded() { var query_context = getQueryContext(); PF_initOIUnderbar(query_context,":QS:default","","JRN"); PF_insertOIUnderbar(0); }; if (window.addEventListener) { window.addEventListener('load', fnc_onDomLoaded, false); } else if (window.attachEvent) { window.attachEvent('onload', fnc_onDomLoaded); } var gaJsHost = (("https:" == document.location.protocol) ? "https://ssl." : "http://www."); document.write(unescape("%3Cscript src='" + gaJsHost + "google-analytics.com/ga.js' type='text/javascript'%3E%3C/script%3E")); try { var pageTracker = _gat._getTracker("UA-189672-16"); pageTracker._setDomainName(".oxfordjournals.org"); pageTracker._trackPageview(); } catch(err) {} http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png British Medical Bulletin Oxford University Press

Social and biological pathways linking early life and adult disease

British Medical Bulletin, Volume 53 (1) – Jan 1, 1997

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Publisher
Oxford University Press
Copyright
Copyright © 2015 Oxford University Press
ISSN
0007-1420
eISSN
1471-8391
DOI
bmb;53/1/210
Publisher site
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Abstract

Evidence is presented for a pathways model linking early life factors and adult disease, which takes account of the inter-relationships between social and biological risks throughout the lifecourse. Few studies, if any, have yet recorded adequate birth to death information which could be used to quantify the effects of different factors and their timing. Hence, there is only limited understanding of the extent to which biological and social risks experienced at different life stages combine to influence adult disease. However, some of the pathways between early and later life are suggested when evidence from earlier stages of the lifecourse is linked to that from studies at older ages, in which adult disease risk factors have been established. Further support for pathway effects is provided by studies showing that health outcomes of early biological insults can depend on the subsequent social and biological environment. Thus, it is argued that adult disease will be more fully understood when account is taken of the combined effects of social and biological risk occurring at different life stages. © The British Council « Previous | Next Article » Table of Contents This Article Br Med Bull (1997) 53 (1): 210-221. » Abstract Free Full Text (PDF) Free Classifications Article Services Article metrics Alert me when cited Alert me if corrected Find similar articles Similar articles in Web of Science Similar articles in PubMed Add to my archive Download citation Request Permissions Disclaimer Citing Articles Load citing article information Citing articles via CrossRef Citing articles via Scopus Citing articles via Web of Science Citing articles via Google Scholar Google Scholar Articles by Power, C. Articles by Hertzman, C. Search for related content PubMed PubMed citation Articles by Power, C. Articles by Hertzman, C. Related Content Load related web page information Share Email this article CiteULike Delicious Facebook Google+ Mendeley Twitter What's this? Search this journal: Advanced » Current Issue September 2015 115 (1) Alert me to new issues The Journal About this journal Rights & Permissions Dispatch date of the next issue We are mobile – find out more Journals Career Network Impact factor: 3.658 5-Yr impact factor: 4.420 Editor-in-Chief Dr Norman J Vetter View full editorial board Alerting Services Email table of contents Email Advance Access CiteTrack XML RSS feed Corporate Services Reprints Supplements For Authors Open access options for authors - visit Oxford Open Self-archiving policy Instructions to authors This journal enables compliance with the NIH Public Access Policys Policy var taxonomies = ("MED00010"); Most Most Read Hazards of heavy metal contamination Health hazards and waste management Noise pollution: non-auditory effects on health Environmental pollution and the global burden of disease Contaminants in drinking water: Environmental pollution and health » View all Most Read articles Most Cited The thrifty phenotype hypothesis: Type 2 diabetes INTERHEMISPHERIC DIFFERENCES IN THE LOCALIZATION OF PSYCHOLOGICAL PROCESSES IN MAN DEVELOPMENTAL CYCLES AND BIOLOGY OF PATHOGENIC TRYPANOSOMES METHODS FOR THE INVESTIGATION OF PERIPHERAL BLOOD FLOW Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease » View all Most Cited articles Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department. Online ISSN 1471-8391 - Print ISSN 0007-1420 Copyright © 2015 Oxford University Press Oxford Journals Oxford University Press Site Map Privacy Policy Cookie Policy Legal Notices Frequently Asked Questions Other Oxford University Press sites: Oxford University Press Oxford Journals China Oxford Journals Japan Academic & Professional books Children's & Schools Books Dictionaries & Reference Dictionary of National Biography Digital Reference English Language Teaching Higher Education Textbooks International Education Unit Law Medicine Music Online Products & Publishing Oxford Bibliographies Online Oxford Dictionaries Online Oxford English Dictionary Oxford Language Dictionaries Online Oxford Scholarship Online Reference Rights and Permissions Resources for Retailers & Wholesalers Resources for the Healthcare Industry Very Short Introductions World's Classics function fnc_onDomLoaded() { var query_context = getQueryContext(); PF_initOIUnderbar(query_context,":QS:default","","JRN"); PF_insertOIUnderbar(0); }; if (window.addEventListener) { window.addEventListener('load', fnc_onDomLoaded, false); } else if (window.attachEvent) { window.attachEvent('onload', fnc_onDomLoaded); } var gaJsHost = (("https:" == document.location.protocol) ? "https://ssl." : "http://www."); document.write(unescape("%3Cscript src='" + gaJsHost + "google-analytics.com/ga.js' type='text/javascript'%3E%3C/script%3E")); try { var pageTracker = _gat._getTracker("UA-189672-16"); pageTracker._setDomainName(".oxfordjournals.org"); pageTracker._trackPageview(); } catch(err) {}

Journal

British Medical BulletinOxford University Press

Published: Jan 1, 1997

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