Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Optimizing screening procedures for Staphylococcus aureus nasal carriage in patients on haemodialysis.

Optimizing screening procedures for Staphylococcus aureus nasal carriage in patients on... Abstract BACKGROUND: So far it remains unclear what the optimal screening method for detection of S. aureus nasal carriage in patients on haemodialysis is with regard to number of cultures performed, culture interval, and necessity of a broth-enrichment procedure. METHODS: A prospective, uncontrolled study was performed at the renal unit of a tertiary care centre, including all haemodialysis patients (n=91) attending the unit during the study period. The purpose was to determine the optimal screening method for S. aureus nasal carriage in patients on haemodialysis. RESULTS: When compared to the conventional culture method, inclusion of a broth-enrichment procedure increased the number of cultures positive for S. aureus significantly (31 vs 24%, P<0.0001). Of 91 patients 37% were S. aureus carriers (defined as at least 1 of 5 cultures positive), 33% were stable carriers (defined as at least 2 of 5 cultures positive). Fourth and 5th cultures, taken at subsequent dialysis sessions, captured only two additional carriers (6% of all carriers). With respect to culture results and identification of carrier status a short (1-h) and a long (>24-h) sampling procedure showed no significantly different results. CONCLUSIONS: S. aureus nasal carriage in haemodialysis patients can be conveniently established with three nasal cultures taken with 1-h intervals, and the inclusion of a broth-enrichment procedure. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nephrology Dialysis Transplantation Oxford University Press

Optimizing screening procedures for Staphylococcus aureus nasal carriage in patients on haemodialysis.

Loading next page...
 
/lp/oxford-university-press/optimizing-screening-procedures-for-staphylococcus-aureus-nasal-rexW8MwIxA

References (9)

Publisher
Oxford University Press
ISSN
0931-0509
eISSN
1460-2385
DOI
10.1093/ndt/13.5.1256
Publisher site
See Article on Publisher Site

Abstract

Abstract BACKGROUND: So far it remains unclear what the optimal screening method for detection of S. aureus nasal carriage in patients on haemodialysis is with regard to number of cultures performed, culture interval, and necessity of a broth-enrichment procedure. METHODS: A prospective, uncontrolled study was performed at the renal unit of a tertiary care centre, including all haemodialysis patients (n=91) attending the unit during the study period. The purpose was to determine the optimal screening method for S. aureus nasal carriage in patients on haemodialysis. RESULTS: When compared to the conventional culture method, inclusion of a broth-enrichment procedure increased the number of cultures positive for S. aureus significantly (31 vs 24%, P<0.0001). Of 91 patients 37% were S. aureus carriers (defined as at least 1 of 5 cultures positive), 33% were stable carriers (defined as at least 2 of 5 cultures positive). Fourth and 5th cultures, taken at subsequent dialysis sessions, captured only two additional carriers (6% of all carriers). With respect to culture results and identification of carrier status a short (1-h) and a long (>24-h) sampling procedure showed no significantly different results. CONCLUSIONS: S. aureus nasal carriage in haemodialysis patients can be conveniently established with three nasal cultures taken with 1-h intervals, and the inclusion of a broth-enrichment procedure.

Journal

Nephrology Dialysis TransplantationOxford University Press

Published: May 1, 1998

There are no references for this article.