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Molecular insights into the initiation of sporulation in Gram-positive bacteria: new technologies for an old phenomenon⋆

Molecular insights into the initiation of sporulation in Gram-positive bacteria: new technologies... AbstractThe last decade has witnessed extensive, and widespread, changes in scientific technologies that have impacted significantly upon the study of the life sciences. Arguably, the biggest advances in our comprehension of simple and complex biological processes have come as a consequence of obtaining the complete DNA sequence of organisms. It is likely that we will become accustomed to hearing of quantum leaps in the study and understanding of the biology of higher eukaryotes in the coming years, now that (near) complete genome sequences are available for man, mouse and rat. In this review, we will discuss the impact of genome sequence data, and the use of new scientific technologies that have emerged largely as consequence of the availability of this information, on the study of the master regulator of sporulation, Spo0A, in low G + C Gram-positive endospore-forming bacteria. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png FEMS Microbiology Reviews Oxford University Press

Molecular insights into the initiation of sporulation in Gram-positive bacteria: new technologies for an old phenomenon⋆

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References (114)

Publisher
Oxford University Press
Copyright
© 2005 Federation of European Microbiological Societies.
ISSN
0168-6445
eISSN
1574-6976
DOI
10.1016/j.fmrre.2004.10.003
Publisher site
See Article on Publisher Site

Abstract

AbstractThe last decade has witnessed extensive, and widespread, changes in scientific technologies that have impacted significantly upon the study of the life sciences. Arguably, the biggest advances in our comprehension of simple and complex biological processes have come as a consequence of obtaining the complete DNA sequence of organisms. It is likely that we will become accustomed to hearing of quantum leaps in the study and understanding of the biology of higher eukaryotes in the coming years, now that (near) complete genome sequences are available for man, mouse and rat. In this review, we will discuss the impact of genome sequence data, and the use of new scientific technologies that have emerged largely as consequence of the availability of this information, on the study of the master regulator of sporulation, Spo0A, in low G + C Gram-positive endospore-forming bacteria.

Journal

FEMS Microbiology ReviewsOxford University Press

Published: Apr 9, 2005

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