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Is re-modification of Ross operation necessary?

Is re-modification of Ross operation necessary? Letters to the Editor / European Journal of Cardio-Thoracic Surgery 233 Is re-modification of Ross operation necessary? Ismail Yurekli*, Mert Kestelli, Orhan Gokalp and Ali Gurbuz Department of Cardiovascular Surgery, Izmir Ataturk Education and Research Hospital, Izmir, Turkey * Corresponding author. Tel.: +90-505-5251202; fax: +90-232-2431530; e-mail: ismoyurekli@yahoo.com (I. Yurekli). Received 9 March 2011; accepted 13 May 2011 Keywords: Aortic valve � Dilatation � Autograft This is an interesting article [1]. We enthusiastically support the REFERENCES use of Dacron graft in Ross operation to prevent aortic dilation in long term. The diameter of sinus of Valsalva increases by 16% [1] Brown JW, Ruzmetov M, Shahriari AP, Rodefeld MD, Mahomed Y, Turrentine MW. Modification of the Ross aortic valve replacement during systole in native aorta [2] (although thicker than native to prevent late autograft dilatation. Eur J Cardiothorac Surg 2010;37: pulmonary artery). As the Dacron graft could not change its 1002–7. diameter during systole, we think that this may cause an increase [2] Thubrikar MJ, Nolan SP, Aouad J, Deck JD. Stress sharing between in incidence of aneurysm/dissection formation. To overcome this the sinus and leaflets of canine aortic valve. Ann Thorac Surg 1986;42: 434–40. problem, would it be more convenient to insert Dacron graft between coronary buttons? doi:10.1016/j.ejcts.2011.05.029 The corresponding author of the original article [1] was invited to reply but did not respond. Tackling reperfusion injury after cardiopulmonary bypass with tetrahydrobiopterin: new therapeutic potentials for this phenylketonuria drug? Yanti Octavia, Natascha L. Assman and An L. Moens Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht, The Netherlands * Corresponding author. Address: Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht, R Delbeyelaan 25, 6202 AZ Maastricht, The Netherlands. Tel.: +31 43 387 1587; fax: +31 43 387 2870. e-mail: an.moens@mumc.nl (A.L. Moens). Received 1 March 2011; accepted 12 April 2011 Keywords: Tetrahydrobiopterin � Cardiopulmonary bypass � Myocardial function � Endothelial function � Nitric oxide synthases monoxide and natriuretic peptides [2], which are also released in Szabo et al. [1] demonstrated that administration of tetrahydro- ischemia/reperfusion damage [3]. In addition, plasma arterial biopterin (BH4) during early reperfusion improves cardiopul- monary recovery after cardioplegic arrest and extracorporeal cGMP is correlated with atrial natriuretic peptide levels, and its circulation in dogs. Application of BH4 restored myocardial, production is secondary to an enhancement of the local tissue endothelial, and pulmonary function and increases plasma cyclic cGMP of the vascular bed [4]. It is required to measure natriuret- guanosine monophosphatase (cGMP) levels. ic peptide to exclude this as another factor of cGMP production. Szabo et al. concluded that the beneficial effect of BH4 Moreover, there are several more direct ways to evaluate eNOS on reperfusion injury after cardiopulmonary bypass can be coupling, such as eNOS monomer/dimer analysis, eNOS activity, explained by recoupling of endothelial nitric oxide synthase eNOS- dependent superoxide generation, and quantification of (eNOS), as supported by increased cGMP levels measured by BH4 and BH2 levels [5]. radioimmunoassay. However, there are many factors that can In addition, it is not clear whether the dose of BH4 that is used in cause induction of cGMP other than NO, such as carbon the study of Szabo et al. increases myocardial and endothelial levels of BH4. Subsequently, it is unclear whether the improved left- The corresponding author of the original article [1] was invited to reply but did not respond. ventricular function is due to improved myocyte function or is LETTERS TO THE EDITOR http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Cardio-Thoracic Surgery Oxford University Press

Is re-modification of Ross operation necessary?

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References (12)

Publisher
Oxford University Press
Copyright
The Author 2011. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved
Subject
LETTERS TO THE EDITOR
ISSN
1010-7940
eISSN
1873-734X
DOI
10.1016/j.ejcts.2011.05.029
pmid
21708470
Publisher site
See Article on Publisher Site

Abstract

Letters to the Editor / European Journal of Cardio-Thoracic Surgery 233 Is re-modification of Ross operation necessary? Ismail Yurekli*, Mert Kestelli, Orhan Gokalp and Ali Gurbuz Department of Cardiovascular Surgery, Izmir Ataturk Education and Research Hospital, Izmir, Turkey * Corresponding author. Tel.: +90-505-5251202; fax: +90-232-2431530; e-mail: ismoyurekli@yahoo.com (I. Yurekli). Received 9 March 2011; accepted 13 May 2011 Keywords: Aortic valve � Dilatation � Autograft This is an interesting article [1]. We enthusiastically support the REFERENCES use of Dacron graft in Ross operation to prevent aortic dilation in long term. The diameter of sinus of Valsalva increases by 16% [1] Brown JW, Ruzmetov M, Shahriari AP, Rodefeld MD, Mahomed Y, Turrentine MW. Modification of the Ross aortic valve replacement during systole in native aorta [2] (although thicker than native to prevent late autograft dilatation. Eur J Cardiothorac Surg 2010;37: pulmonary artery). As the Dacron graft could not change its 1002–7. diameter during systole, we think that this may cause an increase [2] Thubrikar MJ, Nolan SP, Aouad J, Deck JD. Stress sharing between in incidence of aneurysm/dissection formation. To overcome this the sinus and leaflets of canine aortic valve. Ann Thorac Surg 1986;42: 434–40. problem, would it be more convenient to insert Dacron graft between coronary buttons? doi:10.1016/j.ejcts.2011.05.029 The corresponding author of the original article [1] was invited to reply but did not respond. Tackling reperfusion injury after cardiopulmonary bypass with tetrahydrobiopterin: new therapeutic potentials for this phenylketonuria drug? Yanti Octavia, Natascha L. Assman and An L. Moens Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht, The Netherlands * Corresponding author. Address: Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht, R Delbeyelaan 25, 6202 AZ Maastricht, The Netherlands. Tel.: +31 43 387 1587; fax: +31 43 387 2870. e-mail: an.moens@mumc.nl (A.L. Moens). Received 1 March 2011; accepted 12 April 2011 Keywords: Tetrahydrobiopterin � Cardiopulmonary bypass � Myocardial function � Endothelial function � Nitric oxide synthases monoxide and natriuretic peptides [2], which are also released in Szabo et al. [1] demonstrated that administration of tetrahydro- ischemia/reperfusion damage [3]. In addition, plasma arterial biopterin (BH4) during early reperfusion improves cardiopul- monary recovery after cardioplegic arrest and extracorporeal cGMP is correlated with atrial natriuretic peptide levels, and its circulation in dogs. Application of BH4 restored myocardial, production is secondary to an enhancement of the local tissue endothelial, and pulmonary function and increases plasma cyclic cGMP of the vascular bed [4]. It is required to measure natriuret- guanosine monophosphatase (cGMP) levels. ic peptide to exclude this as another factor of cGMP production. Szabo et al. concluded that the beneficial effect of BH4 Moreover, there are several more direct ways to evaluate eNOS on reperfusion injury after cardiopulmonary bypass can be coupling, such as eNOS monomer/dimer analysis, eNOS activity, explained by recoupling of endothelial nitric oxide synthase eNOS- dependent superoxide generation, and quantification of (eNOS), as supported by increased cGMP levels measured by BH4 and BH2 levels [5]. radioimmunoassay. However, there are many factors that can In addition, it is not clear whether the dose of BH4 that is used in cause induction of cGMP other than NO, such as carbon the study of Szabo et al. increases myocardial and endothelial levels of BH4. Subsequently, it is unclear whether the improved left- The corresponding author of the original article [1] was invited to reply but did not respond. ventricular function is due to improved myocyte function or is LETTERS TO THE EDITOR

Journal

European Journal of Cardio-Thoracic SurgeryOxford University Press

Published: Jan 1, 2012

Keywords: Aortic valve Dilatation Autograft

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