Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/oxford-university-press/expression-of-lewis-x-is-associated-with-poor-prognosis-in-triple-Kh8F4J8FYt
References (47)
-
S. Schröder, W. Schwarz, W. Rehpenning, H. Dralle, V. Bay, W. Böcker (2004)
Leu-M1 immunoreactivity and prognosis in medullary carcinomas of the thyroid glandJournal of Cancer Research and Clinical Oncology, 114
-
R. Dent, M. Trudeau, K. Pritchard, W. Hanna, H. Kahn, C. Sawka, L. Lickley, E. Rawlinson, P. Sun, S. Narod (2007)
Triple-Negative Breast Cancer: Clinical Features and Patterns of RecurrenceClinical Cancer Research, 13
-
R. Königsberg, G. Pfeiler, Tatjana Klement, Nicole Hammerschmid, A. Brunner, R. Zeillinger, C. Singer, C. Dittrich (2012)
Tumor characteristics and recurrence patterns in triple negative breast cancer: a comparison between younger (<65) and elderly (≥65) patients.European journal of cancer, 48 16
-
References -
C. Liedtke, C. Mazouni, K. Hess, F. André, A. Tordai, J. Mejia, W. Symmans, A. González-Angulo, B. Hennessy, Marjorie Green, M. Cristofanilli, G. Hortobagyi, L. Pusztai (2008)
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26 8
-
Fabien Calvo, P. Martin, N. Jabrane, P. Crémoux, Henri Magdelenat (1987)
Human breast cancer cells share antigens with the myeloid monocyte lineage.British Journal of Cancer, 56
-
P. Farmer, H. Bonnefoi, P. Anderle, D. Cameron, P. Wirapati, V. Bécette, S. André, M. Piccart, M. Campone, E. Brain, G. MacGrogan, T. Petit, J. Jassem, F. Bibeau, E. Blot, J. Bogaerts, M. Aguet, J. Bergh, R. Iggo, M. Delorenzi (2009)
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancerNature Medicine, 15
-
(2013)
Am J Clin Pathol -
B. Keam, S. Im, Kyung-Hun Lee, Sae-Won Han, D. Oh, J. Kim, Se-Hoon Lee, W. Han, Dong-Wan Kim, Tae-You Kim, I. Park, D. Noh, D. Heo, Y. Bang (2011)
Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosisBreast Cancer Research : BCR, 13
-
Katherina Zabicki, J. Colbert, F. Dominguez, M. Gadd, K. Hughes, Julie Jones, M. Specht, J. Michaelson, Barbara Smith (2006)
Breast Cancer Diagnosis in Women ≤ 40 versus 50 to 60 Years: Increasing Size and Stage Disparity Compared With Older Women Over TimeAnnals of Surgical Oncology, 13
-
T. Shirahama, M. Ikoma, T. Muramatsu, Y. Ohi (1992)
Expression of SSEA-1 carbohydrate antigen correlates with stage, grade and metastatic potential of transitional cell carcinoma of the bladder.The Journal of urology, 148 4
-
B. Hennessy, A. González-Angulo, K. Stemke‐Hale, M. Gilcrease, S. Krishnamurthy, Ju-Seog Lee, J. Fridlyand, A. Sahin, R. Agarwal, C. Joy, Wenbin Liu, D. Stivers, K. Baggerly, M. Carey, A. Lluch, C. Monteagudo, Xiaping He, V. Weigman, C. Fan, J. Palazzo, G. Hortobagyi, L. Nolden, Nicholas Wang, V. Valero, J. Gray, C. Perou, G. Mills (2009)
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.Cancer research, 69 10
-
Fumito Ito, Alfred Chang (2013)
Current Status and Future Directions -
M. Cheang, D. Voduc, C. Bajdik, S. Leung, S. McKinney, S. Chia, C. Perou, T. Nielsen (2008)
Basal-Like Breast Cancer Defined by Five Biomarkers Has Superior Prognostic Value than Triple-Negative PhenotypeClinical Cancer Research, 14
-
N. Neuhold, F. Längle, M. Gnant, U. Hollenstein, B. Niederle (2005)
Relationship of CD15 immunoreactivity and prognosis in sporadic medullary thyroid carcinomaJournal of Cancer Research and Clinical Oncology, 118
-
Nakagoe T., Fukushima K., Itoyanagi N., Ikuta Y., Oka T., Nagayasu T., Ayabe H., Hara S., Ishikawa H., Minami H. (2002)
Expression of ABH/Lewis-related antigens as prognostic factors in patients with breast cancerJournal of Cancer Research and Clinical Oncology, 128
-
L. Dirix, G. Romieu, L. Provencher, D. Grimes, L. Viana, A. Paterson, L. Mauriac, A. Kirsch, S. Pernas, D. Miles (2009)
Safety of bevacizumab (BV) plus docetaxel (D) in patients (pts) with locally recurrent (LR) or metastatic breast cancer (mBC) who developed brain metastases during the AVADO phase III study.Cancer Research, 69
-
Debra Winkeljohn (2008)
Triple-negative breast cancer.Clinical journal of oncology nursing, 12 6
-
J. Mordoh, C. Silva, M. Albarellos, A. Bravo, C. Kairiyama (1995)
Phase I Clinical Trial in Cancer Patients of a New Monoclonal Antibody FC‐2.15 Reacting with Tumor Proliferating CellsJournal of Immunotherapy, 17
-
H. Fredholm, S. Eaker, J. Frisell, L. Holmberg, I. Fredriksson, H. Lindman (2009)
Breast Cancer in Young Women: Poor Survival Despite Intensive TreatmentPLoS ONE, 4
-
T. Jacobs, A. Gown, H. Yaziji, Melissa Barnes, S. Schnitt (1999)
Specificity of HercepTest in determining HER-2/neu status of breast cancers using the United States Food and Drug Administration-approved scoring system.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 17 7
-
B. Weigelt, J. Reis-Filho (2009)
Histological and molecular types of breast cancer: is there a unifying taxonomy?Nature Reviews Clinical Oncology, 6
-
E. Dabelsteen (1996)
REVIEW ARTICLE. CELL SURFACE CARBOHYDRATES AS PROGNOSTIC MARKERS IN HUMAN CARCINOMASThe Journal of Pathology, 179
-
E. Montagna, P. Maisonneuve, N. Rotmensz, G. Cancello, M. Iorfida, A. Balduzzi, V. Galimberti, P. Veronesi, A. Luini, G. Pruneri, L. Bottiglieri, M. Mastropasqua, A. Goldhirsch, G. Viale, M. Colleoni (2013)
Heterogeneity of triple-negative breast cancer: histologic subtyping to inform the outcome.Clinical breast cancer, 13 1
-
W. Han, S. Kim, In Park, D. Kang, Sung-Won Kim, Y. Youn, S. Oh, K. Choe, D. Noh (2004)
Young age: an independent risk factor for disease-free survival in women with operable breast cancerBMC Cancer, 4
-
Adeline Whitney, M. Diehn, S. Popper, Ash Alizadeh, Jennifer Boldrick, D. Relman, P. Brown (2003)
Individuality and variation in gene expression patterns in human bloodProceedings of the National Academy of Sciences of the United States of America, 100
-
D. Waugh, Catherine Wilson (2008)
The Interleukin-8 Pathway in CancerClinical Cancer Research, 14
-
O. Gluz, C. Liedtke, N. Gottschalk, L. Pusztai, U. Nitz, N. Harbeck (2009)
Triple-negative breast cancer--current status and future directions.Annals of oncology : official journal of the European Society for Medical Oncology, 20 12
-
C. Perou (2010)
Molecular stratification of triple-negative breast cancers.The oncologist, 15 Suppl 5
-
M. Son, K. Woolard, D. Nam, Jeongwu Lee, H. Fine (2009)
SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma.Cell stem cell, 4 5
-
Z. Shi, L. McIntyre, B. Knowles, D. Solter, Y. Kim (1984)
Expression of a carbohydrate differentiation antigen, stage-specific embryonic antigen 1, in human colonic adenocarcinoma.Cancer research, 44 3
-
M. Elola, M. Capurro, M. Barrio, P. Coombs, Maureen Taylor, K. Drickamer, J. Mordoh (2006)
Lewis x Antigen Mediates Adhesion of Human Breast Carcinoma Cells to Activated Endothelium. Possible Involvement of the Endothelial Scavenger Receptor C-type LectinBreast Cancer Research and Treatment, 101
-
M. Colleoni, N. Rotmensz, C. Robertson, L. Orlando, G. Viale, G. Renne, A. Luini, P. Veronesi, M. Intra, R. Orecchia, G. Catalano, V. Galimberti, F. Nolè, Giovanni Martinelli, A. Goldhirsch (2002)
Very young women (<35 years) with operable breast cancer: features of disease at presentation.Annals of oncology : official journal of the European Society for Medical Oncology, 13 2
-
B. Kreike, Marieke Kouwenhove, H. Horlings, B. Weigelt, H. Peterse, H. Bartelink, M. Vijver (2007)
Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomasBreast cancer research : BCR, 9
-
C. Perou, T. Sørlie, M. Eisen, M. Rijn, S. Jeffrey, Christian Rees, J. Pollack, D. Ross, H. Johnsen, L. Akslen, Ø. Fluge, Alexander Pergamenschikov, Cheryl Williams, Shirley Zhu, P. Lønning, A. Børresen-Dale, P. Brown, D. Botstein (2000)
Molecular portraits of human breast tumoursNature, 406
-
L. Masmiquel, M. Castro-Forns, I. Torres, A. García, Maria Vidal, Rafael Simó (1997)
Leu-M1 immunoreactivity and phaeochromocytoma.Journal of Clinical Pathology, 50
-
T. Read, M. Fogarty, S. Markant, R. McLendon, Zhengzheng Wei, D. Ellison, P. Febbo, R. Wechsler-Reya (2009)
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.Cancer cell, 15 2
-
C. Desmedt, B. Haibe-Kains, P. Wirapati, M. Buyse, D. Larsimont, Gianluca Bontempi, M. Delorenzi, M. Piccart, C. Sotiriou (2008)
Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular SubtypesClinical Cancer Research, 14
-
T. Narita, H. Funahashi, Y. Satoh, Tadashi Watanabe, H. Takagi, J. Sakamoto (1993)
Association of expression of blood group‐related carbohydrate antigens with prognosis in breast cancerCancer, 71
-
B. Konety, B. Ballou, R. Jaffe, J. Singh, J. Reiland, T. Hakala (1997)
Expression of SSEA-1 (Lewis(x)) on transitional cell carcinoma of the bladder.Urologia internationalis, 58 2
-
S. Schröder, W. Schwarz, W. Rehpenning, T. Löning, W. Böcker (2004)
Prognostic significance of Leu-M1 immunostaining in papillary carcinomas of the thyroid glandVirchows Archiv A, 411
-
B. Siwek, D. Larsimont, M. Lacroix, J. Body (1998)
Establishment and characterization of three new breast‐cancer cell linesInternational Journal of Cancer, 76
-
S. Itzkowitz, Z. Shi, Y. Kim (1986)
Heterogeneous expression of two oncodevelopmental antigens, CEA and SSEA-1, in colorectal cancerThe Histochemical Journal, 18
-
L. Monhollen, C. Morrison, F. Ademuyiwa, R. Chandrasekhar, T. Khoury (2012)
Pleomorphic lobular carcinoma: a distinctive clinical and molecular breast cancer typeHistopathology, 61
-
Address reprint requests to Dr Gong: Dept of Pathology -
P. Farmer, Hervé Bonnefoi, V. Bécette, M. Tubiana‐Hulin, P. Fumoleau, D. Larsimont, G. MacGrogan, J. Bergh, D. Cameron, Darlene Goldstein, S. Duss, Anne-Laure Nicoulaz, C. Brisken, M. Fiche, Mauro Delorenzi, R. Iggo (2005)
Identification of molecular apocrine breast tumours by microarray analysisOncogene, 24
-
A. Kadota, M. Masutani, M. Takei, T. Horie (1999)
Evaluation of expression of CD15 and sCD15 in non-small cell lung cancer.International journal of oncology, 15 6
- Publisher
- Oxford University Press
- Copyright
- © Published by Oxford University Press.
- ISSN
- 0002-9173
- eISSN
- 1943-7722
- DOI
- 10.1309/AJCP2E6QNDIDPTTC
- pmid
- 23690116
- Publisher site
- See Article on Publisher Site
Abstract
The Lewis X (LeX) antigen is a prognostic marker in certain solid tumors and has been proposed as a therapeutic target. Immunohistochemical analyses were performed to retrospectively examine the prognostic impact of LeX expression in 158 patients with triple-negative breast cancer (TNBC). Twenty-three (14.5%) patients were LeX-positive. Multivariate analysis showed that LeX positivity was an independent poor prognostic factor for recurrence-free survival (RFS) and overall survival (OS) (P = .037 and P = .024, respectively). LeX expression was a prognostic factor for survival in stage I/II and stage III TNBCs. Subgroup analysis according to age showed that LeX positivity was only associated with poor RFS and OS in younger patients with TNBC (age < 50 years) (P < .001 and P < .001, respectively). Our results suggest that LeX expression is an independent prognostic factor for RFS and OS in younger patients with TNBC.
Journal
American Journal of Clinical Pathology – Oxford University Press
Published: Jun 1, 2013