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J. Annegers, S. Blakley, W. Hauser, L. Kurland (1990)
Recurrence of febrile convulsions in a population-based cohortEpilepsy Research, 5
D. Kapfhamer, H. Sweet, D. Sufalko, S. Warren, K. Johnson, M. Burmeister (1996)
The neurological mouse mutations jittery and hesitant are allelic and map to the region of mouse chromosome 10 homologous to 19p13.3.Genomics, 35 3
L. Ashworth, M. Batzer, B. Brandriff, E. Branscomb, P. Jong, Emilio Garcia, J. Garnes, L. Gordon, J. Lamerdin, G. Lennon, H. Mohrenweiser, A. Olsen, T. Slezak, A. Carrano (1995)
An integrated metric physical map of human chromosome 19Nature Genetics, 11
G. Lathrop, J. Lalouel (1984)
Easy calculations of lod scores and genetic risks on small computers.American journal of human genetics, 36 2
W. Hauser (1994)
The Prevalence and Incidence of Convulsive Disorders in ChildrenEpilepsia, 35
J. Stanhope, J. Brody, E. Brink, C. Morris (1972)
Convulsions among the Chamorro people of Guam, Mariana islands. II. Febrile convulsions.American journal of epidemiology, 95 3
T. Ciulla, R. Sklar, S. Hauser (1988)
A simple method for DNA purification from peripheral blood.Analytical biochemistry, 174 2
(1995)
Febrile convulsions: is seizure duration the most important predictor of temporal lobe epilepsy? Brain
L. Gordon, A. Bergmann, M. Christensen, L. Danganan, D. Lee, L. Ashworth, D. Nelson, A. Olsen, H. Mohrenweiser, A. Carrano (1995)
A 30-Mb metric fluorescence in situ hybridization map of human chromosome 19q.Genomics, 30 2
C. Verity, N. Butler, J. Golding (1985)
Febrile convulsions in a national cohort followed up from birth. I--Prevalence and recurrence in the first five years of life.British Medical Journal (Clinical research ed.), 290
C. Dib, S. Fauré, C. Fizames, D. Samson, N. Drouot, A. Vignal, P. Millasseau, S. Marc, J. Kazan, E. Seboun, M. Lathrop, G. Gyapay, J. Morissette, J. Weissenbach (1996)
A comprehensive genetic map of the human genome based on 5,264 microsatellitesNature, 380
G. Collin, A. Münch, J. Mu, J. Naggert, A. Olsen, P. Nishina (1996)
Physical and genetic mapping of novel microsatellite polymorphisms on human chromosome 19.Genomics, 37 1
S. Rich, J. Annegers, W. Hauser, V. Anderson (1987)
Complex segregation analysis of febrile convulsions.American journal of human genetics, 41 2
A. Berg, S. Shinnar, S. Shinnar, W. Hauser, M. Alemany, E. Shapiro, M. Salomon, E. Crain (1992)
A prospective study of recurrent febrile seizures.The New England journal of medicine, 327 16
E. Lander, P. Green (1987)
Construction of multilocus genetic linkage maps in humans.Proceedings of the National Academy of Sciences of the United States of America, 84 8
R. Gardiner (1990)
Genes and epilepsy.Journal of Medical Genetics, 27
A. Berg, S. Shinnar, W. Hauser, John Leventhal (1990)
Predictors of recurrent febrile seizures: a metaanalytic review.The Journal of pediatrics, 116 3
(1981)
FEBRILE SEIZURES IN CHILDHOODInPharma, 273
J. Murray, K. Buetow, J. Weber, S. Ludwigsen, T. Scherpbier-Heddema, F. Manion, John Quillen, V. Sheffield, S. Sunden, G. Duyk, J. Weissenbach, Borbála Gyapay, C. Dib, Jean Morrissette, G. Lathrop, A. Vignal, N. Matsunami, S. Gerken, Roberta Melis, H. Albertsen, R. Plaetke, S. Odelberg, D. Cohen, H. Cann (1994)
A comprehensive human linkage map with centimorgan density. Cooperative Human Linkage Center (CHLC).Science, 265 5181
J. Stanhope, J. Brody, E. Brink (1972)
Convulsions among the Chamorro people of Guam, Mariana islands. I. Seizure disorders.American journal of epidemiology, 95 3
R. Wallace, S. Berkovic, R. Howell, G. Sutherland, J. Mulley (1996)
Suggestion of a major gene for familial febrile convulsions mapping to 8q13-21.Journal of Medical Genetics, 33
F. Cendes, M. Cook, C. Watson, F. Andermann, D. Fish, S. Shorvon, P. Bergin, S. Free, F. Dubeau, D. Arnold (1995)
Frequency and characteristics of dual pathology in patients with lesional epilepsyNeurology, 45
J. Annegers, W. Hauser, S. Shirts, L. Kurland (1987)
Factors prognostic of unprovoked seizures after febrile convulsions.The New England journal of medicine, 316 9
Arne Nystuen, Paul Benke, Joy Merren, E. Stone, V. Sheffield (1996)
A cerebellar ataxia locus identified by DNA pooling to search for linkage disequilibrium in an isolated population from the Cayman Islands.Human molecular genetics, 5 4
J. Weber, Z. Wang, K. Hansen, M. Stephenson, C. Kappel, S. Salzman, P. Wilkie, B. Keats, N. Dracopoli, B. Brandriff (1993)
Evidence for human meiotic recombination interference obtained through construction of a short tandem repeat-polymorphism linkage map of chromosome 19.American journal of human genetics, 53 5
(1994)
Science
G. Gyapay, J. Morissette, A. Vignal, C. Dib, C. Fizames, P. Millasseau, S. Marc, G. Bernardi, M. Lathrop, J. Weissenbach (1994)
The 1993–94 Généthon human genetic linkage mapNature Genetics, 7
T. Tsuboi (1976)
Polygenic Inheritance of Epilepsy and Febrile Convulsions: Analysis based on a Computational ModelBritish Journal of Psychiatry, 129
Febrile convulsions are a common form of childhood seizure. It is estimated that between 2 and 5% of children will have a febrile convulsion before the age of 5. It has long been recognized that there is a significant genetic component for susceptibility to this type of seizure. Wallace, Berkovic and co-workers recently reported linkage of a putative autosomal dominant febrile convulsion gene to chromosome 8q13–21. We report here another autosomal dominant febrile convulsion locus on chromosome 19p. Linkage analysis in this large multi-generational family gave a maximum pairwise lod score of 4.52 with marker Mfd120 at locus D19S177. Linkage to the chromosome 8 locus was excluded in this family. Haplotype analysis using both affected and unaffected family members indicates that this febrile convulsion gene, which we call FEB2, can be localized to an 11.7 cM, 1–2 Mb section of chromosome 19p13.3, between loci D19S591 and D19S395.
Human Molecular Genetics – Oxford University Press
Published: Jan 1, 1998
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