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References (14)
-
S. Frasier, S. Frasier, J. Hilburn, J. Hilburn, Nancy Matthews, Nancy Matthews (1967)
The serum growth-hormone response to hypoglycemia in dwarfism.The Journal of pediatrics, 71 5
-
L. Underwood, Kazuo Azumi, S. Voina, J. Wyk (1971)
Growth hormone levels during sleep in normal and growth hormone deficient children.Pediatrics, 48 6
-
E. Spanos, D. Barrett, I. Macintyre, J. Pike, E. Safilian, M. Haussler (1978)
Effect of growth hormone on vitamin D metabolismNature, 273
-
STUART Lancer, NELSON Bowser, G. Hargis, Gerald Williams (1976)
The effect of growth hormone on parathyroid function in rats.Endocrinology, 98 5
-
A. Gilman (1970)
A protein binding assay for adenosine 3':5'-cyclic monophosphate.Proceedings of the National Academy of Sciences of the United States of America, 67 1
-
P. Henneman, A. Forbes, M. Moldawer, E. Dempsey, E. Carroll (1960)
Effects of human growth hormone in man.The Journal of clinical investigation, 39
-
J. Gertner, R. Horst, A. Broadus, H. Rasmussen, M. Genel (1979)
Parathyroid function and vitamin D metabolism during human growth hormone replacement.The Journal of clinical endocrinology and metabolism, 49 2
-
C. Arnaud, H. Tsao, T. Littledike (1971)
Radioimmunoassay of human parathyroid hormone in serum.The Journal of clinical investigation, 50 1
-
P. Eskildsen, B. Lund, O. Sørensen, Bi. Lund, J. Bishop, Anthony Norman (1979)
Acromegaly and vitamin D metabolism: effect of bromocriptine treatment.The Journal of clinical endocrinology and metabolism, 49 3
-
J. Eisman, A. Hamstra, B. Kream, H. DeLuca (1976)
A sensitive, precise, and convenient method for determination of 1,25-dihydroxyvitamin D in human plasma.Archives of biochemistry and biophysics, 176 1
-
V. Weldon, S. Gupta, G. Klingensmith, W. Clarke, S. Duck, M. Haymond, A. Pagliara (1975)
Evaluation of growth hormone release in children using arginine and L-dopa in combination.The Journal of pediatrics, 87 4
-
S. Edelstein, M. Charman, D. Lawson, E. Kodicek (1974)
Competitive protein-binding assay for 25-hydroxycholecalciferol.Clinical science and molecular medicine, 46 2
-
Charles Pak, Masahiro Ohata, E. Lawrence, William Snyder (1974)
The hypercalciurias. Causes, parathyroid functions, and diagnostic criteria.The Journal of clinical investigation, 54 2
-
C. Pak, C. Fetner, J. Townsend, L. Brinkley, C. Northcutt, D. Barilla, M. Kadesky, P. Peters (1978)
Evaluation of calcium urolithiasis in ambulatory patients: comparison of results with those of inpatient evaluation.The American journal of medicine, 64 6
- Publisher
- Oxford University Press
- Copyright
- Copyright © 1980 by The Endocrine Society
- ISSN
- 0021-972X
- eISSN
- 1945-7197
- DOI
- 10.1210/jcem-51-2-321
- Publisher site
- See Article on Publisher Site
Abstract
Abstract The mechanism by which GH stimulates intestinal calcium absorption was explored. In this study, seven children with idiopathic GH deficiency were studied before and during GH therapy while they were maintained on the same metabolic diet. After 5–14 months of GH administration, fractional intestinal calcium absorption increased from 0.364 ± 0.114 to 0.449 ± 0.159 (P < 0.01), and serum 1,25-dihydroxyvitamin D decreased from 63.7 ± 19.3 to 46.7 ± 17.8 pg/ml (P < 0.025). Serum immunoreactive parathyroid hormone, urinary cAMP, serum 24,25-dihydroxyvitamin D, and 25-hydroxyvitamin D did not change significantly.The data suggest that GH does not directly influence parathyroid hormone or vitamin D metabolism. The possibility that relative intestinal resistance to 1,25-dihydroxyvitaminD exists in patients with GH deficiency is considered. (J Clin Endocrinol Metab51: 321, 1980) This content is only available as a PDF. Author notes * This work was supported by USPHS Grants ROl-AM-16061, P50 AM-20543, MOl-RR-00633, and ROl-HD-10909-01 and Training Grant AM-07307-02. Copyright © 1980 by The Endocrine Society
Journal
Journal of Clinical Endocrinology and Metabolism – Oxford University Press
Published: Aug 1, 1980