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Chemical interactions with herpes simplex type 2 virus: enhancement of transformation by norharman

Chemical interactions with herpes simplex type 2 virus: enhancement of transformation by norharman Abstract The effects of the comutagen norharman on herpes simplex virus type 2 growth transformation was studied in 3T3 cells. Pre-exposure but not post-exposure of the cells to 0.5 to 10 μg of norharman per ml of cell culture media resulted in a nearly three-fold enhancement in transforming activity. These results suggest that certain environmental chemicals may interact with cells creating an increased possibility of transformation by herpes viruses. © 1982 IRL Press Limited http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Carcinogenesis Oxford University Press

Chemical interactions with herpes simplex type 2 virus: enhancement of transformation by norharman

Abstract

Abstract The effects of the comutagen norharman on herpes simplex virus type 2 growth transformation was studied in 3T3 cells. Pre-exposure but not post-exposure of the cells to 0.5 to 10 μg of norharman per ml of cell culture media resulted in a nearly three-fold enhancement in transforming activity. These results suggest that certain environmental chemicals may interact with cells creating an increased possibility of transformation by herpes viruses. © 1982 IRL Press Limited
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