Abstract The stability of RNAs represent a crucial point for cell life in that these molecules code for proteins and also play structural and regulatory functions. In this review, we will mainly focus on RNA stability and its connection with cell death and aging. In addition, we will consider the interaction of RNAs with ribonucleoprotein (RPN) complexes, such as P-bodies and Stress granules, as well as the role of non-coding RNAs. Finally, we will mention some correlations between RNA and diseases, considering yeast as a simple model system for the study of human cancer and neurodegenerative disorders. yeast, cell death, aging, diseases, RNA stability, ncRNAs © FEMS 2018. All rights reserved. For permissions, please e-mail: firstname.lastname@example.org
FEMS Yeast Research – Oxford University Press
Published: Apr 19, 2018
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