Primary Brain Myxoma, an Unusual Tumor of Meningeal Origin: Case Report

Primary Brain Myxoma, an Unusual Tumor of Meningeal Origin: Case Report AbstractOBJECTIVE AND IMPORTANCE:Primary myxoma of the central nervous system is an extremely rare tumor arising from cells of primitive mesenchymal origin. Only two cases of primary intracranial myxoma have been described previously. We report a patient with a primary myxoma originating from the right frontoparietal convexity dura, which we studied in detail with diagnostic imaging and pathological analysis.CLINICAL PRESENTATION:A female adolescent presented to the emergency department with a 3-day history of mild headache, abdominal pain, and intermittent left-sided focal motor seizures. Neurological examination was remarkable for left leg hyperreflexia and difficulty with tandem gait. Cranial computed tomography and magnetic resonance imaging demonstrated an inhomogeneously enhancing mass in the right frontoparietal region.INTERVENTION:A right frontoparietal craniotomy was performed. During surgery, a tumor appearing similar to a typical convexity meningioma was completely removed along with the dural attachment.CONCLUSION:The patient had an uneventful recovery and returned to normal activity. Primary intracranial myxoma should be distinguished from other meningeal tumors and metastatic cardiac myxoma by appropriate pathological analysis and cardiac evaluation. A circumscribed myxoma completely excised with adequate dural margin carries a good prognosis for surgical cure. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neurosurgery Oxford University Press

Primary Brain Myxoma, an Unusual Tumor of Meningeal Origin: Case Report

Primary Brain Myxoma, an Unusual Tumor of Meningeal Origin: Case Report

1 66 Graham et al. was noted. Findings of the general phys­ Primary Brain Myxoma, an Unusual ical examination were within normal lim­ its. The cranial CT scan demonstrated an Tumor of Meningeal O rigin: Case Report irregularly enhancing ring lesion in the right frontoparietal region with associated mass effect (Fig. 1). Our initial impression Jon F. Graham, M.D., Stanley Y.T. Loo, M.D., was that this lesion probably represented a glial tumor, based on its ring enhance­ Aiko Matoba, M.D. ment as revealed by computed tomogra­ Neurosurgery Service (JFG) and Department of Pathology (SYTL), Hawaii Permanente phy; less likely, it could be an unusual Medical Group; Department of Surgery (JPG), University of Hawaii, Honolulu, Hawaii; and infectious or parasitic process. Department of Neurosurgery (AM), Tokyo Women's Medical College, Tokyo, Japan A loading dose of phenytoin was ad­ ministered, and the seizures resolved af­ ter a few focal motor episodes during O BJECTIVE AND IM PORTANCE: Primary myxoma of the central nervous the first 24 hours of hospitalization. Ad­ system is an extremely rare tumor arising from cells of primitive mesen­ mission laboratory results including uri­ chymal origin. Only two cases of primary intracranial myxoma have been nalysis, complete blood cell count, coag­ described previously. W e report a patient with a primary myxoma orig­ ulation profile, and serum electrolytes inating from the right frontoparietal convexity dura, which we studied in were unremarkable. An infectious dis­ detail with diagnostic imaging and pathological analysis. ease evaluation including tuberculin CLINICAL PRESENTATION: A female adolescent presented to the emergency test, cysticercosis serology, and stool for department with a 3-day history of mild headache, abdominal pain, and ova and parasites was negative. The pa­ intermittent left-sided focal motor seizures. Neurological examination was tient was treated...
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Publisher
Oxford University Press
Copyright
© Published by Oxford University Press.
ISSN
0148-396X
eISSN
1524-4040
D.O.I.
10.1097/00006123-199907000-00039
Publisher site
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Abstract

AbstractOBJECTIVE AND IMPORTANCE:Primary myxoma of the central nervous system is an extremely rare tumor arising from cells of primitive mesenchymal origin. Only two cases of primary intracranial myxoma have been described previously. We report a patient with a primary myxoma originating from the right frontoparietal convexity dura, which we studied in detail with diagnostic imaging and pathological analysis.CLINICAL PRESENTATION:A female adolescent presented to the emergency department with a 3-day history of mild headache, abdominal pain, and intermittent left-sided focal motor seizures. Neurological examination was remarkable for left leg hyperreflexia and difficulty with tandem gait. Cranial computed tomography and magnetic resonance imaging demonstrated an inhomogeneously enhancing mass in the right frontoparietal region.INTERVENTION:A right frontoparietal craniotomy was performed. During surgery, a tumor appearing similar to a typical convexity meningioma was completely removed along with the dural attachment.CONCLUSION:The patient had an uneventful recovery and returned to normal activity. Primary intracranial myxoma should be distinguished from other meningeal tumors and metastatic cardiac myxoma by appropriate pathological analysis and cardiac evaluation. A circumscribed myxoma completely excised with adequate dural margin carries a good prognosis for surgical cure.

Journal

NeurosurgeryOxford University Press

Published: Jul 1, 1999

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