In Reply: Quality of Life After Motor Cortex Stimulation: Clinical Results and Systematic Review of the Literature

In Reply: Quality of Life After Motor Cortex Stimulation: Clinical Results and Systematic Review... CORRESPONDENCE Technological Development (CNPq; Conselho Nacional de Desenvolvi- In Reply: Quality of Life After Motor Cortex mento Científico e Tecnológico; 400 201/2012-7). Devices were donated by Stimulation: Clinical Results and Systematic St Jude Medical. Dr Hamani has received honoraria from St Jude Medical and Review of the Literature Medtronic. To the Editor: We thank Dr Alwardat and colleagues for the comments on 2 Daniella Parravano, RN our manuscript. As can be appraised in our review, measures Daniel Ciampi A. de Andrade, MD, PhD of quality of life in the studies pooled for analysis were often Erich T. Fonoff, MD, PhD conducted in an open label fashion. Only a few trials used Bernardo A. Monaco, MD statistical analyses to blindly quantify on/off stimulation changes. Jessie Navarro, MD In this context, the majority of the literature provides class III Lin T. Yeng, MD evidence as far as quality of life measures are considered. Though Manoel J. Teixeira, MD, PhD only keywords were used, search terms were presented and the ∗ ‡ Clement Hamani, MD, PhD reasons for excluding articles were reported. General biases were Division of Neurosurgery noted in the discussion, along with the potential occurrence of a Department of Neurology placebo effect. University of São Paulo Medical School After starting the review, we were surprised to see that only São Paulo, Brazil 6 studies fulfilled our inclusion criteria and decided to analyze Division of Neurosurgery open label data from patients exiting a clinical trial currently Sunnybrook Health Sciences Centre being conducted in our institution. Our results show that MCS Toronto, Canada significantly improves visual analog pain scores and quality of life measures. Interestingly, no correlation was found between the 2, REFERENCES suggesting that changes in quality of life after motor cortex stimu- lation cannot be simply explained by the analgesic effects of this 1. Alwardat M, Khraiwash Y, Etoom M. Letter: Quality of life after motor cortex therapy. As it stands, our study provides class III data, corrob- stimulation. Neurosurgery. 2018. doi: 10.1093/neuros/nyy249 [Published online ahead of print]. orating previously published data. That said, it contrasts with 2. Parravano DC, Ciampi DA, Fonoff ET, et al. Quality of life after previous reports, inasmuch as it was primarily focused on quality motor cortex stimulation: clinical results and systematic review of the liter- of life. ature. Neurosurgery. 2018. doi: 10.1093/neuros/nyy060 [published online ahead of print]. Disclosures This study was sponsored in part with funds from the Science without 10.1093/neuros/nyy250 Border program of the Brazilian National Council for Scientific and NEUROSURGERY VOLUME 0 | NUMBER 0 | 2018 | 1 Downloaded from https://academic.oup.com/neurosurgery/advance-article-abstract/doi/10.1093/neuros/nyy250/5025494 by Ed 'DeepDyve' Gillespie user on 11 July 2018 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neurosurgery Oxford University Press

In Reply: Quality of Life After Motor Cortex Stimulation: Clinical Results and Systematic Review of the Literature

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Publisher
Congress of Neurological Surgeons
Copyright
Copyright © 2018 by the Congress of Neurological Surgeons
ISSN
0148-396X
eISSN
1524-4040
D.O.I.
10.1093/neuros/nyy250
Publisher site
See Article on Publisher Site

Abstract

CORRESPONDENCE Technological Development (CNPq; Conselho Nacional de Desenvolvi- In Reply: Quality of Life After Motor Cortex mento Científico e Tecnológico; 400 201/2012-7). Devices were donated by Stimulation: Clinical Results and Systematic St Jude Medical. Dr Hamani has received honoraria from St Jude Medical and Review of the Literature Medtronic. To the Editor: We thank Dr Alwardat and colleagues for the comments on 2 Daniella Parravano, RN our manuscript. As can be appraised in our review, measures Daniel Ciampi A. de Andrade, MD, PhD of quality of life in the studies pooled for analysis were often Erich T. Fonoff, MD, PhD conducted in an open label fashion. Only a few trials used Bernardo A. Monaco, MD statistical analyses to blindly quantify on/off stimulation changes. Jessie Navarro, MD In this context, the majority of the literature provides class III Lin T. Yeng, MD evidence as far as quality of life measures are considered. Though Manoel J. Teixeira, MD, PhD only keywords were used, search terms were presented and the ∗ ‡ Clement Hamani, MD, PhD reasons for excluding articles were reported. General biases were Division of Neurosurgery noted in the discussion, along with the potential occurrence of a Department of Neurology placebo effect. University of São Paulo Medical School After starting the review, we were surprised to see that only São Paulo, Brazil 6 studies fulfilled our inclusion criteria and decided to analyze Division of Neurosurgery open label data from patients exiting a clinical trial currently Sunnybrook Health Sciences Centre being conducted in our institution. Our results show that MCS Toronto, Canada significantly improves visual analog pain scores and quality of life measures. Interestingly, no correlation was found between the 2, REFERENCES suggesting that changes in quality of life after motor cortex stimu- lation cannot be simply explained by the analgesic effects of this 1. Alwardat M, Khraiwash Y, Etoom M. Letter: Quality of life after motor cortex therapy. As it stands, our study provides class III data, corrob- stimulation. Neurosurgery. 2018. doi: 10.1093/neuros/nyy249 [Published online ahead of print]. orating previously published data. That said, it contrasts with 2. Parravano DC, Ciampi DA, Fonoff ET, et al. Quality of life after previous reports, inasmuch as it was primarily focused on quality motor cortex stimulation: clinical results and systematic review of the liter- of life. ature. Neurosurgery. 2018. doi: 10.1093/neuros/nyy060 [published online ahead of print]. Disclosures This study was sponsored in part with funds from the Science without 10.1093/neuros/nyy250 Border program of the Brazilian National Council for Scientific and NEUROSURGERY VOLUME 0 | NUMBER 0 | 2018 | 1 Downloaded from https://academic.oup.com/neurosurgery/advance-article-abstract/doi/10.1093/neuros/nyy250/5025494 by Ed 'DeepDyve' Gillespie user on 11 July 2018

Journal

NeurosurgeryOxford University Press

Published: May 30, 2018

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