SCIENCE TIMES Unfortunately, this approach does not T-Vim trajectory, while sensory side exhibit an annual hemorrhage rate of account for interindividual anatomic effects were elicited in the target of the 2.5% (95% CI 1.3%-5.1%). Previous variability, and MRI limits visualization of conventional trajectory due to off-target hemorrhage has shown to be the most individual thalamic nuclei. Individualized sensory thalamus stimulation (Figures C significant hemorrhagic risk factor, while tractography may provide more robust and D). age, sex, location, size, and multiplicity anatomic data for targeting thalamic These findings support the use of deter- are less relevant. Hyperpermeability of nuclei. A recent study by Sammartino ministic tractography that relies on the CCM vessels occurs via the inactivation et al presents a novel method for deter- ML and PT internal landmarks to locate of ccm1, 2, or 3 genes and the subse- mining the tractography-based Vim target Vim in clinical settings. In particular, quent increase in RhoA activity and (T-Vim) for ultimate use in the clinical this new algorithm is an attractive alter- Rho-associated coiled-coil-forming kinase treatment of essential tremor. native to the existing probabilistic tractog- (ROCK). Multiple therapies based on T-Vim uses the pyramidal tract (PT) and raphy algorithms that are
Neurosurgery – Oxford University Press
Published: May 1, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
It’s easy to organize your research with our built-in tools.
All the latest content is available, no embargo periods.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud