Development of a Clinically Useful Algorithm for Tractography-Based Ventral Intermediate Nucleus Targeting

Development of a Clinically Useful Algorithm for Tractography-Based Ventral Intermediate Nucleus... SCIENCE TIMES ssential tremor, characterized by efficacy depends on precise targeting of Development of a a persistent, bilateral kinetic and the Vim, particularly areas with a high Clinically Useful postural tremor, is a common degree of connectivity among regions neurological disorder with a prevalence implicated in the “tremor network,” Algorithm for of 0.9% in the general population, and including the ipsilateral motor cortex and up to 4.6% in those over age 65. Deep contralateral cerebellum. Indirect targeting Tractography-Based brain stimulation (DBS) and thalam- is a common method used to locate Ventral Intermediate otomy of the ventral intermediate nucleus the Vim target that superimposes atlas- (Vim) of the thalamus can successfully derived coordinates onto a patient’s unique Nucleus Targeting control upper limb tremor. Treatment magnetic resonance imaging (MRI) scan. Figure. A, The Vim ROI was determined by creating 2 lines (blue lines) at the borders of the ML (blue outline) and PT (red outline) as identified using the tractography technique. One line is drawn at the medial border of the PT, and the other at the anterior border of the ML. At the intersection of these lines a 3-mm ROI representing the Vim is placed (yellow circle). B, Coronal and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neurosurgery Oxford University Press

Development of a Clinically Useful Algorithm for Tractography-Based Ventral Intermediate Nucleus Targeting

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Publisher
Oxford University Press
Copyright
Copyright © 2017 by the Congress of Neurological Surgeons
ISSN
0148-396X
eISSN
1524-4040
D.O.I.
10.1093/neuros/nyx099
Publisher site
See Article on Publisher Site

Abstract

SCIENCE TIMES ssential tremor, characterized by efficacy depends on precise targeting of Development of a a persistent, bilateral kinetic and the Vim, particularly areas with a high Clinically Useful postural tremor, is a common degree of connectivity among regions neurological disorder with a prevalence implicated in the “tremor network,” Algorithm for of 0.9% in the general population, and including the ipsilateral motor cortex and up to 4.6% in those over age 65. Deep contralateral cerebellum. Indirect targeting Tractography-Based brain stimulation (DBS) and thalam- is a common method used to locate Ventral Intermediate otomy of the ventral intermediate nucleus the Vim target that superimposes atlas- (Vim) of the thalamus can successfully derived coordinates onto a patient’s unique Nucleus Targeting control upper limb tremor. Treatment magnetic resonance imaging (MRI) scan. Figure. A, The Vim ROI was determined by creating 2 lines (blue lines) at the borders of the ML (blue outline) and PT (red outline) as identified using the tractography technique. One line is drawn at the medial border of the PT, and the other at the anterior border of the ML. At the intersection of these lines a 3-mm ROI representing the Vim is placed (yellow circle). B, Coronal and

Journal

NeurosurgeryOxford University Press

Published: May 1, 2017

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