Age and Ageing 2018; 47: 625 © The Author(s) 2018. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: firstname.lastname@example.org Clinical Reminder Clinical correlation of blood culture results Conﬂict of interest None declared. A 78-year-old female was treated with ﬂucloxacillin for leg cel- lulitis. This was changed to amoxicillin for a week following 1 1 1 ABHAY KUMAR DAS ,PAUL DODDS ,ELEANOR BRUNT , isolation of Enterococcus faecium in the blood cultures. She had 2 JONATHAN WAREING aortic murmur and changed bowel habit. Four months later, Mid Yorkshire Hospitals NHS Trust—Medicine for the Elderly Leeds Medical School—Faculty of Medicine the GP referred her to a nephrologist for progressive renal Address correspondence to: Abhay Kumar Das, impairment with chronic anaemia. She had weakly positive Mid Yorkshire Hospitals NHS Trust—Medicine for the Elderly, cANCA (PR3 1.8) and negative anti-GBM antibody. She also 22 Peregrine Avenue, Morley, Leeds LS27 8TD, UK. developed progressive thrombocytopenia and CRP remained Tel: +44-1924-816140; Fax: +44-1924-816136. Email: email@example.com elevated. She was re-admitted from haematology clinic for evaluation. The blood culture again isolated E. faecium which remained sensitive to amoxicillin. She died from a cardiac arrest the same day. Post-mortem revealed aortic valve endocarditis. References Enterococci are more prevalent in older patients with 1. Dhawan V. Infective endocarditis in elderly patients. Current infective endocarditis . Glomerulonephritis is common in infectious disease reports. Curr Infect Dis Rep 2003; 5: bacterial endocarditis and prolonged inﬂammatory activity 285–92. may lead to positive cANCA . Prolonged guided anti- 2. Ghosh GC, Sharma B, Katageri B et al. ANCA positivity biotic therapy, of up to 6 weeks duration, is recommended in a patient with infective endocarditis-associated glomerulo- for the successful treatment of bacterial endocarditis . nephritis: a diagnostic dilemma. Yale J Biol Med 2014; 87: 373–7. 3. Habib G, Lancellotti P, Antunes M et al. ESC Guidelines Key points for the management of infective endocarditis: the Task Force for the Management of Infective Endocarditis of the � Signiﬁcance of blood culture result. European Society of Cardiology. Eur Heart J 2015; 36: � Use of appropriate antibiotic. 3075–128. � Consider bacterial endocarditis. � Longer duration of treatment for endocarditis. doi: 10.1093/ageing/afy063 Published electronically 25 April 2018 Downloaded from https://academic.oup.com/ageing/article-abstract/47/4/625/4985484 by Ed 'DeepDyve' Gillespie user on 26 June 2018
Age and Ageing – Oxford University Press
Published: Apr 25, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera