Abstracts

Abstracts This content is only available as a PDF. © 1996 The European Society of Cardiology http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Heart Journal Oxford University Press

Abstracts

European Heart Journal , Volume 17 (Abstract_Supplement) – Aug 1, 1996

Abstracts

Day 2 Monday, August 26, 1996 Downloaded from https://academic.oup.com/eurheartj/article-abstract/17/Abstract_Supplement/1/596680 by Ed 'DeepDyve' Gillespie user on 04 February 2018 Biology of cardiac overload 3 BIOLOGY OF CARDIAC OVERLOAD 1961 Cardiac hypertrophy modifies repolarization differently in endocardial and epicardial myocytes S.J. Shipsey, S.M. Bryant, G. Hart. Department of Cardiovascular Medicine, /941 Regional differences in mRNA and protein expression . University of Oxford, OX3 9DU, UK pattern of the inhibitory G protein Gio:2 and sarccplasmtc reticulum Ca + ATPase in heart failure due to dilated Hypertrophy is associated with prolongation of action potential duration (APD) cardiomyopathy in ventricular myocytes. In view of endocardial/epicardial differences in APD in guinea pigs, we have studied changes in AP characteristics associated with I.C. Van Gelder 1, M. Flesch, F. Schiffer, P. Schnabel, H.J.G.M. Crijns 1, hypertrophy in these regions. Mild cardiac hypertrophy (HTY) was induced in M. Bohm, University Hospital Cologne, Germany; 1 Thoraxcenter, University guinea pigs by abdominal aortic constriction. Sham operated animals were Hospital Groningen, The Netherlands controls (CON). Myocytes were isolated from basal sub-endocardium (endo) Abnormalities in the if-adrenergic neuroeffector mechanisms and in the intra­ and apical sub-epicardium (epi) of the left ventricular free wall 159 ± 1 days post 2+ cellular Ca handling play a crucial role in the pathogenesis of congestive operation. Membrane voltage was measured using the switch-clamp technique heart failure. Most previous investigations were performed in left ventricular with high resistance microelectrodes (:::::: 20 MQ). Data are expressed as mean (LV) myocardium and conclusions were extrapolated to the ':fail.i~g heart" in ± sem(n), ANOVA was used to assess statistical significance. Hypertrophy was general. The aim was to investigate whether...
Loading next page...
 
/lp/ou_press/abstracts-VoHTo2mYZR
Publisher
Oxford University Press
Copyright
© 1996 The European Society of Cardiology
ISSN
0195-668X
eISSN
1522-9645
D.O.I.
10.1093/eurheartj/17.Abstract_Supplement.1
Publisher site
See Article on Publisher Site

Abstract

This content is only available as a PDF. © 1996 The European Society of Cardiology

Journal

European Heart JournalOxford University Press

Published: Aug 1, 1996

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off