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findings demonstrate that blood cells of the lymphoid and myeloid lineages contribute to various non - haematopoietic tissues by forming rare fusion hybrids, but almost exclusively in response to injuries ...
that this could create conditions of increased chance for acquisition of pre-leukaemogenic rearrangements/mutations in both lymphoid and myeloid lineages during foetal haematopoiesis, contributing to the increased ...
in embryonic development, established disease and specialised non - haematopoietic niches. The mechanistic insights provided by accurate models will help identify viable novel therapeutic options. © 2021 ...
and nine high-grade Non -Hodgkin's lymphomas), in a panel of 16 leukaemia cell lines, in normal mature haematopoietic cells of both myeloid and lymphoid lineage , as well as in CD34+ haematopoietic progenitor ...
an important role in the survival, proliferation and differentiation of haematopoietic progenitor cells 1 . It is expressed in >90% of myeloid malignancies, nearly 100% in B‐ lineage childhood acute lymphoblastic ...
) are non ‐coding, small RNAs, which post‐transcriptionally control gene expression of multiple target genes. The miR‐181 family is known to control haematopoietic lineage differentiation. Here, we study ...
with fluorescence protein ZsGreen-labelled ECs were treated with Sugen/hypoxia (Su/Hx) combination to induce PH, the percentage of ZsGreen+ haematopoietic cells in the peripheral blood, primarily of myeloid lineage ...
progenitors (MPPs), which is the first branch point of myeloid and lymphoid lineage . In this model, common myeloid progenitors can differentiate into bipotent Mgk/erythroid progenitors (MEPs), and MEPs ...
of action of these non - lymphoid regulatory cells as they relate to the induction or maintenance of tolerance in organ transplantation. alloreactivity, regulatory cells, transplantation Myeloid dendritic cells ...
prompted a reevaluation of the proposed function of PU.1 during hematopoiesis. During hematopoiesis, PU.1 is required for development along the lymphoid and myeloid lineages but needs to be downregulated ...
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