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2008 |doi:10.1038/nature06933 LETTERS Multi - genetic events collaboratively contribute to Pten - null leukaemia stem-cell formation 1 2 1 1 1 5 6 Wei Guo , Joseph L. Lasky , Chun-Ju Chang , Sherly Mosessian ...
, and vector-transduced HSPCs. GFP+ cell percentages were analyzed 4 months after transplantation. *Indicates significant difference between two groups. (p ...
]. Some genes were found to contribute to cancerogenesis through conferring cell growth advantage, referred to as drivers [8–10]. However, patients seldom harbor exactly the same driving genetic alterations ...
. The management of these tumors remains very challenging, especially as they are usually diagnosed in early childhood. Overall prognosis is dismal, and there is no consensus on their treatment. Molecular genetic ...
was observed in some patients, but no clinically significant event has been observed to date. Prophylaxis for Pneumocystis carinii pneumonia was not required. Conclusions: Continuous dose-intense TMZ 50 mg/m2 ...
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