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- cell engineering studies, many of which assume that mouse skin stays homogeneous during lengthy experiments. Vol 451 | 17 January 2008 |doi:10.1038/nature06457 LETTERS Cyclic dermal BMP signalling ...
. Proc Natl Acad Sci USA 2007 ; 104 : 10063 – 10068 . Google Scholar Crossref Search ADS PubMed WorldCat 43 Plikus MV , Mayer JA, de la Cruz D et al. Cyclic dermal BMP signalling regulates stem cell ...
of Wnt signaling pathways in the regulation of skin development, hair follicle morphogenesis, and governance of epidermal stem cells during tissue homeostasis. The spatial and temporal interconnections ...
2006 ; 20 : 276 – 281 . Google Scholar Crossref Search ADS PubMed WorldCat 19 Plikus MV , Mayer JA, de la Cruz D et al. Cyclic dermal BMP signalling regulates stem cell activation during hair ...
of HF stem /progenitor cells . BMP Signaling Regulates β‐Catenin Activity Inducing EP‐SC Activation Partially Through the PTEN‐Akt Cascade To investigate the molecular mechanism by which BMP signaling ...
signaling in both of these processes in vivo [18-20]. Moreover, during HFs morphogenesis, there is abundant expression of different BMP ligands in the epithelial progenitor cells , the differentiating HF ...
between BMP and WNT in hfSCs regulation . Our findings lend support to our hypothesis that inhibition of BMP signaling primes the HF toward activation in a Wnt-ligand-dependent manner and reveal direct ...
and peroxisome proliferator- activated receptor γ (PPARγ) signals appear to be crucial in the genesis of SGs. Hair follicle stem cells deficient for β-catenin showed signs of massive sebocyte differentiation [22 ...
for the cyclic regeneration of HFs, during which it switches from phases of growth (anagen) via regression (catagen) to relative quiescence (telogen) [7],[16]. HF entry into anagen requires the activation of HF ...
, Mayer JA, de la Cruz D et al. Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration . Nature 2008 ; 451 : 340 – 344 . Google Scholar Crossref Search ADS PubMed WorldCat 25 ...
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