Access the full text.
Sign up today, get DeepDyve free for 14 days.
(1994)
Inaugural lecture at the Friedrich Schiller University
W. Hamilton (1964)
The genetical evolution of social behaviour. I.Journal of theoretical biology, 7 1
L. Parr, F. Waal (1999)
Visual kin recognition in chimpanzeesNature, 399
J. McCaskill, R. Füchslin, S. Altmeyer (2001)
The Stochastic Evolution of Catalysts in Spatially Resolved Molecular Systems, 382
S. Wright (1977)
Evolution and the Genetics of Populations, Volume 3: Experimental Results and Evolutionary Deductions
C. Bresch, U. Niesert, D. Harnasch (1980)
Hypercycles, parasites and packages.Journal of theoretical biology, 85 3
I. Hofacker, W. Fontana, P. Stadler, L. Bonhoeffer, M. Tacker, Philipp Schuster (1994)
Fast folding and comparison of RNA secondary structuresMonatshefte für Chemie / Chemical Monthly, 125
E. Szathmáry, László Demeter (1987)
Group selection of early replicators and the origin of life.Journal of theoretical biology, 128 4
A. Isles, M. Baum, D. Ma, E. Keverne, Nicholas Allen (2001)
Genetic imprinting: Urinary odour preferences in miceNature, 409
J. Lehn (2002)
Toward complex matter: Supramolecular chemistry and self-organizationProceedings of the National Academy of Sciences of the United States of America, 99
M. Kimura (1983)
Diffusion model of intergroup selection, with special reference to evolution of an altruistic character.Proceedings of the National Academy of Sciences of the United States of America, 80 20
M. Eigen, P. Schuster (2009)
The Hypercycle: A principle of natural self-organization
J. McCaskill (1997)
Spatially resolved in vitro molecular ecology.Biophysical chemistry, 66 2-3
K. Harding, J. McNamara (2002)
A Unifying Framework for Metapopulation DynamicsThe American Naturalist, 160
M. Cronhjort, C. Blomberg (1997)
Cluster compartmentalization may provide resistance to parasites for catalytic networksPhysica D: Nonlinear Phenomena, 101
M. Eigen (1971)
Selforganization of matter and the evolution of biological macromoleculesNaturwissenschaften, 58
Artiicial Life
S. Altmeyer, J. McCaskill (2001)
Error threshold for spatially resolved evolution in the quasispecies model.Physical review letters, 86 25
M. Boerlijst, P. Hogeweg (1991)
Spiral wave structure in pre-biotic evolution: hypercycles stable against parasitesPhysica D: Nonlinear Phenomena, 48
(1998)
The role of kin selection theory on the explanation of biological altruism: A critical review
M. Eigen, J. McCaskill, P. Schuster (1988)
Molecular quasi-species.The Journal of Physical Chemistry, 92
S. Kauffman (1971)
Gene regulation networks: a theory for their global structure and behaviors.Current topics in developmental biology, 6 6
A. Babajide, R. Farber, I. Hofacker, J. Inman, A. Lapedes, P. Stadler (2001)
Exploring protein sequence space using knowledge-based potentials.Journal of theoretical biology, 212 1
J. Fritz, Marko Baller, H. Lang, H. Rothuizen, P. Vettiger, E. Meyer, H. Güntherodt, C. Gerber, J. Gimzewski (2000)
Translating biomolecular recognition into nanomechanics.Science, 288 5464
S. Levin, R. Paine (1974)
Disturbance, patch formation, and community structure.Proceedings of the National Academy of Sciences of the United States of America, 71 7
McCaskill Folding Stabilizes the Evolution of Catalysts
Sequence folding is known to determine the spatial structure and catalytic function of proteins and nucleic acids. We show here that folding also plays a key role in enhancing the evolutionary stability of the intermolecular recognition necessary for the prevalent mode of catalytic action in replication, namely, in trans , one molecule catalyzing the replication of another copy, rather than itself. This points to a novel aspect of why molecular life is structured as it is, in the context of life as it could be: folding allows limited, structurally localized recognition to be strongly sensitive to global sequence changes, facilitating the evolution of cooperative interactions. RNA secondary structure folding, for example is shown to be able to stabilize the evolution of prolonged functional sequences, using only a part of this length extension for intermolecular recognition, beyond the limits of the (cooperative) error threshold. Such folding could facilitate the evolution of polymerases in spatially heterogeneous systems. This facilitation is, in fact, vital because physical limitations prevent complete sequence-dependent discrimination for any significant-size biopolymer substrate. The influence of partial sequence recognition between biopolymer catalysts and complex substrates is investigated within a stochastic, spatially resolved evolutionary model of trans catalysis. We use an analytically tractable nonlinear master equation formulation called PRESS (McCaskill et al., Biol. Chem. 382: 1343–1363), which makes use of an extrapolation of the spatial dynamics down from infinite dimensional space, and compare the results with Monte Carlo simulations.
Artificial Life – MIT Press
Published: Jan 1, 2004
Keywords: Evolution; catalysis; RNA; altruism; origins of life; recognition
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.