“Whoa! It’s like Spotify but for academic articles.”

Instant Access to Thousands of Journals for just $40/month

Transporter Assays Using Solid Supported Membranes: A Novel Screening Platform for Drug Discovery

Transporters are important targets in drug discovery. However, high throughput-capable assays for this class of membrane proteins are still missing. Here we present a novel drug discovery platform technology based on solid supported membranes. The functional principles of the technology are described, and a sample selection of transporter assays is discussed: the H + -dependent peptide transporter PepT1, the gastric proton pump, and the Na + /Ca 2+ exchanger. This technology promises to have an important impact on the drug discovery process. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png ASSAY and Drug Development Technologies Mary Ann Liebert

Transporter Assays Using Solid Supported Membranes: A Novel Screening Platform for Drug Discovery

Abstract

Transporters are important targets in drug discovery. However, high throughput-capable assays for this class of membrane proteins are still missing. Here we present a novel drug discovery platform technology based on solid supported membranes. The functional principles of the technology are described, and a sample selection of transporter assays is discussed: the H + -dependent peptide transporter PepT1, the gastric proton pump, and the Na + /Ca 2+ exchanger. This technology promises to have an important impact on the drug discovery process.
Loading next page...
1
 
/lp/mary-ann-liebert/transporter-assays-using-solid-supported-membranes-a-novel-screening-qeMzzhXk3a

Sorry, we don’t have permission to share this article on DeepDyve,
but here are related articles that you can start reading right now:

Explore the DeepDyve Library

How DeepDyve Works

Spend time researching, not time worrying you’re buying articles that might not be useful.

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from Springer, Elsevier, Nature, IEEE, Wiley-Blackwell and more.

All the latest content is available, no embargo periods.

See the journals in your area

Simple and Affordable Pricing

14-day free trial. Cancel anytime, with a 30-day money-back guarantee.

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$40/month

Best Deal — 25% off

Annual Plan

  • All the features of the Professional Plan, but for 25% off!
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$30/month
billed annually