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al. High levels of Wilms' tumor gene ( wt1 ) mRNA in acute myeloid leukemias are associated with a worse long-term outcome . Blood 1997 ; 90 : 1217 – 25 . Google Scholar Crossref Search ADS PubMed ...
is a tumor suppressor gene that is generally overexpressed in AML cells, as well as in other types of solid cancers and in hematopoietic malignancies. After birth, a low level of WT1 expression is found ...
include testing for FLT3-internal tandem duplication (ITD) mutations, and may also include testing for mutations in IDH1, IDH2, TET2, WT1 , DNMT3A, and/or TP53, which may be prognostically or therapeutically ...
. The affymetrix gene expression profiling, however, identified another group of genes. In this group, the level of expression changed linearly (either up or down) throughout the period of adult aging from 2 to 24 ...
disease, higher stage and shorter survival, although mesothelioma is an exception to this rule [122, 123]. Finally, PS is a global evaluation of function that predicts outcome in cancer, as well as being ...
transcriptome that change expression with age and may affect taste cell maintenance. Currently, we have focused on two pathways to determine their role in taste cell maintenance. First, we found ...
receiving radiochemotherapy, gained at the cost of relevant toxicity with the PCV regimen. Deletion of 1p and 19q may predict a superior outcome in AO and anaplastic oligoastrocytoma (AOA) in response ...
expression of vascular endothelial growth factors (VEGF) and their receptors (VEGFr). These signals promote aberrant blood vessel formation by recruitment of endothelial cell precursors and facilitate ...
their egress from BM to other sites including spleen and PB. Reduced CXCL12 expression in CML cells can also arise from an additional mechanism. BM CML cells may exhibit increased levels of several cytokines ...
were underexpressed. While generally INI1 was expressed at lower levels in AT/RTs than in all other samples, this did not achieve statistical significance for two groups (normal and meningioma ...
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