Access the full text.
Sign up today, get DeepDyve free for 14 days.
Muin Khoury, Wylie Burke, Elizabeth Thomson (2000)
Genetics and Public Health in the 21st Century
(1980)
Patent Rights in Inventions Made with Federal Assistance. 35 USCS § 202d
B. Starfield, N. Holtzman (1975)
A comparison of effectiveness of screening for phenylketonuria in the United States, United Kingdom and Ireland.The New England journal of medicine, 293 3
Michael Edelstein, M. Abedi, J. Wixon, Richard Edelstein (2004)
Gene therapy clinical trials worldwide 1989–2004—an overviewThe Journal of Gene Medicine, 6
H. Stefánsson, V. Steinthorsdottir, T. Thorgeirsson, J. Gulcher, K. Stefánsson (2004)
Neuregulin 1 and schizophreniaAnnals of Medicine, 36
Michael Farrell, Laura Certain, Philip Farrell (2001)
Genetic counseling and risk communication services of newborn screening programs.Archives of pediatrics & adolescent medicine, 155 2
Sara Selley, J. Donovan, A. Faulkner, J. Coast, D. Gillatt (1997)
Diagnosis, management and screening of early localised prostate cancer.Health technology assessment, 1 2
Jon Merz (1999)
Disease gene patents: overcoming unethical constraints on clinical laboratory medicine.Clinical chemistry, 45 3
P. Gerald (1978)
Genetics, Law, and Social PolicyJAMA, 240
G. Smith, S. Ebrahim (2003)
'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?International journal of epidemiology, 32 1
D. Spigel, H. Burstein (2003)
Trastuzumab regimens for HER2-overexpressing metastatic breast cancer.Clinical breast cancer, 4 5
N. Holtzman, R. Faden, A. Chwalow, S. Horn (1983)
Effect of informed parental consent on mothers' knowledge of newborn screening.Pediatrics, 72 6
Arnold Boonstra, D. Zeeuw, P. Jong, G. Navis (2001)
Role of genetic variability in the renin-angiotensin system in diabetic and nondiabetic renal disease.Seminars in nephrology, 21 6
H. Hakonarson, E. Halapi (2002)
Genetic Analyses in AsthmaAmerican Journal of Pharmacogenomics, 2
S. Nunn (1979)
UNITED STATES GENERAL ACCOUNTING OFFICE
A. Cao (2002)
Carrier screening and genetic counselling in β-thalassemiaInternational Journal of Hematology, 76
Newborn (2000)
Use of Inhaled Nitric OxidePediatrics, 106
M. McKnight (1991)
The Tentative Pregnancy: Prenatal Diagnosis and the Future of MotherhoodPre- and Peri-natal Psychology Journal, 5
(1999)
Newborn Screening Task Force: Serving the family from birth to the medical home: A report from the newborn screening task force convened in Washington DC
C. Browner, J. Shapira (2001)
Testing women, testing the fetusSocial Science & Medicine, 53
T. Evans, R. Evans, M. Barer, T. Marmor (1995)
Why Are Some People Healthy and Others Not? The Determinants of Health of PopulationsHealth and Human Rights, 1
N. Pearce (1996)
[Traditional epidemiology, modern epidemiology and public health].Epidemiologia e prevenzione, 21 2
E. Schoen, John Baker, C. Colby, T. To (2002)
Cost-benefit analysis of universal tandem mass spectrometry for newborn screening.Pediatrics, 110 4
K. Lohmueller, C. Pearce, Malcolm Pike, E. Lander, J. Hirschhorn (2003)
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common diseaseNature Genetics, 33
(2003)
Pediatrix Acquires nation ’ s largest independent laboratory specializing in newborn metabolic screening
P. Sankar, M. Cho, C. Condit, L. Hunt, B. Koenig, P. Marshall, S. Lee, P. Spicer (2004)
Genetic research and health disparities.JAMA, 291 24
L. Andrews (1994)
Assessing Genetic Risks: Implications for Health and Social PolicyBMJ, 309
N. Holtzman (2004)
Effect of expanded newborn screening for biochemical genetic disorders on child outcomes and parental stress.The Journal of pediatrics, 144 5
R. Pollitt, A. Green, C. McCabe, A. Booth, N. Cooper, J. Leonard, J. Nicholl, P. Nicholson, J. Tunaley, N. Virdi (1997)
Neonatal screening for inborn errors of metabolism: cost, yield and outcome.Health technology assessment, 1 7
(1971)
A tale of two thermos bottles : properties of a genetic model for human intelligence
N. Press, H. Carole, Browner (2006)
Collective Silences , Collective Fictions : How Prenatal Diagnostic Testing Became Part of Routine Prenatal Care
H. Rajagopalan, M. Nowak, B. Vogelstein, C. Lengauer (2003)
The significance of unstable chromosomes in colorectal cancerNature Reviews Cancer, 3
Timothy eld (2005)
Confl icts : Gene Patents and Health Care in Canada
C. Browner, Mabel Preloran, N. Press (1996)
The effects of ethnicity, education and an informational video on pregnant women's knowledge and decisions about a prenatal diagnostic screening test.Patient education and counseling, 27 2
(2000)
Enhancing the oversight of genetic tests: Recommendations of the SACGT
(2003)
The Maternal Phenylketonuria Collaborative Study: New developments and the need for new strategies
J. Mckinlay, L. Marceau (1999)
A tale of 3 tails.American journal of public health, 89 3
A. Helgadóttir, A. Manolescu, G. Thorleifsson, S. Gretarsdottir, H. Jonsdóttir, U. Thorsteinsdóttir, N. Samani, G. Gudmundsson, S. Grant, G. Thorgeirsson, S. Sveinbjornsdottir, E. Valdimarsson, Stefán Matthíasson, H. Jóhannsson, Olof Gudmundsdottir, M. Gurney, J. Sainz, Margret Thorhallsdottir, M. Andrésdóttir, M. Frigge, E. Topol, A. Kong, V. Gudnason, H. Hakonarson, J. Gulcher, K. Stefánsson (2004)
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and strokeNature Genetics, 36
E. Girodon-Boulandet, C. Cazeneuve, M. Goossens (2000)
Screening practices for mutations in the CFTR gene ABCC7Human Mutation, 15
W. Thilly (2003)
Have environmental mutagens caused oncomutations in people?Nature Genetics, 34
M. Cassier, D. Stoppa-lyonnet (2005)
L'opposition contre les brevets de Myriad Genetics et leur révocation totale ou partielle en Europe : Premiers enseignementsM S-medecine Sciences, 21
P. Farrell, M. Kosorok, Michael Rock, A. Laxova, Lan Zeng, H. Lai, G. Hoffman, R. Laessig, Mark Splaingard (2001)
Early diagnosis of cystic fibrosis through neonatal screening prevents severe malnutrition and improves long-term growth. Wisconsin Cystic Fibrosis Neonatal Screening Study Group.Pediatrics, 107 1
Maurice Cassier, D. Stoppa-Lyonnet (2005)
[Opposition to Myriad Genetics patents and their total or partial revocation in Europe: early conclusions].Medecine sciences : M/S, 21 6-7
S. Antonarakis, V. McKusick (2000)
OMIM passes the 1,000-disease-gene markNature Genetics, 25
N. Holtzman (2003)
Clinical Utility of Pharmacogenetics and Pharmacogenomics
T. Duster (1990)
Backdoor to eugenics
S. Parthasarathy (2005)
The Patent Is Political: The Consequences of Patenting the BRCA Genes in BritainPublic Health Genomics, 8
R. Cooper, B. Psaty (2003)
Genomics and Medicine: Distraction, Incremental Progress, or the Dawn of a New Age?Annals of Internal Medicine, 138
S. Raeburn (1991)
Proceed with Caution: Predicting Genetic Risks in the Recombinant DNA EraJournal of Medical Ethics, 17
A. Motulsky (1990)
Proceed With Caution: Predicting Genetic Risks in the Recombinant DNA EraJAMA, 263
Sarah Gollust, B. Wilfond, S. Hull (2003)
Direct-to-consumer sales of genetic services on the InternetGenetics in Medicine, 5
J. Venter (2000)
Remarks at the Human Genome AnnouncementFunctional & Integrative Genomics, 1
Sarah Gollust, S. Hull, B. Wilfond (2002)
Limitations of direct-to-consumer advertising for clinical genetic testing.JAMA, 288 14
J. Witte, R. Elston, N. Schork (1996)
Genetic dissection of complex traitsNature Genetics, 12
T. Mckeown (1979)
The Role of Medicine
N. Holtzman (1999)
Are Genetic Tests Adequately Regulated?Science, 286
W. Rothstein (2003)
Public Health and the Risk Factor
A. Gregg, J. Simpson (2002)
Genetic screening for cystic fibrosis.Obstetrics and gynecology clinics of North America, 29 2
N. Holtzman (1970)
Dietary treatment of inborn errors of metabolism.Annual review of medicine, 21
J. Mccormick (1977)
THE ROLE OF MEDICINE. DREAM, MIRAGE OR NEMESIS
G. Rose (1985)
Sick individuals and sick populations.International journal of epidemiology, 14 1
A. Cao (2002)
Carrier screening and genetic counselling in beta-thalassemia.International journal of hematology, 76 Suppl 2
M. Farfel, N. Holtzman (1984)
Education, consent, and counseling in sickle cell screening programs: report of a survey.American journal of public health, 74 4
M. Mahowald (1999)
Promoting Safe and Effective Genetic Testing in the United States: Final Report of the Task Force on Genetic Testing (review)Perspectives in Biology and Medicine, 42
M. Kaback (2000)
Population-based genetic screening for reproductive counseling: the Tay-Sachs disease modelEuropean Journal of Pediatrics, 159
S. Gretarsdottir, G. Thorleifsson, S. Reynisdottir, A. Manolescu, S. Jónsdóttir, T. Jonsdottir, T. Gudmundsdóttir, S. Bjarnadottir, O. Einarsson, H. Gudjonsdottir, M. Hawkins, G. Gudmundsson, H. Gudmundsdóttir, H. Andrason, A. Gudmundsdottir, M. Sigurdardottir, T. Chou, J. Nahmias, S. Goss, S. Sveinbjörnsdóttir, E. Valdimarsson, F. Jakobsson, U. Agnarsson, V. Gudnason, G. Thorgeirsson, J. Fingerle, M. Gurney, D. Gudbjartsson, M. Frigge, A. Kong, K. Stefánsson, J. Gulcher (2003)
The gene encoding phosphodiesterase 4D confers risk of ischemic strokeNature Genetics, 35
T. Marteau, S. Michie, Harriet Drake, M. Bobrow (1995)
Public attitudes towards the selection of desirable characteristics in childrenJournal of Medical Genetics, 32
M. Lewis (1976)
GENETIC SCREENING: PROGRAMS, PRINCIPLES AND RESEARCHCanadian Medical Association Journal, 115
(2002)
Too much for too little? Costly newborn test fuels debate on value. Washington Post 2002, p F01
(1980)
Supreme Court of the United States. 447 US 303; 100 S Ct 2204
A. Clarke (1991)
Is non-directive genetic counselling possible?The Lancet, 338
R. Faden, N. Holtzman, A. Chwalow (1982)
Parental rights, child welfare, and public health: the case of PKU screening.American journal of public health, 72 12
N. Holtzman, R. Kronmal, W. Doorninck, C. Azen, R. Koch (1986)
Effect of age at loss of dietary control on intellectual performance and behavior of children with phenylketonuria.The New England journal of medicine, 314 10
B. Williams-Jones (2003)
Where There’s a Web, There’s a Way: Commercial Genetic Testing and the InternetPublic Health Genomics, 6
James Wilson, M. Weale, Alice Smith, Fiona Gratrix, B. Fletcher, Mark Thomas, N. Bradman, D. Goldstein (2001)
Population genetic structure of variable drug responseNature Genetics, 29
B. Rockhill (2001)
The privatization of risk.American journal of public health, 91 3
H. Levy, S. Albers (2003)
Genetic screening of newborns.Annual review of genomics and human genetics, 1
P. Rowley, S. Loader, Carol Sutera, Margaret Walden, Alyssa Kozyra (1991)
Prenatal screening for hemoglobinopathies. I. A prospective regional trial.American journal of human genetics, 48 3
J. Ioannidis, E. Ntzani, T. Trikalinos, D. Contopoulos-Ioannidis (2001)
Replication validity of genetic association studiesNature Genetics, 29
M. Haffner (2004)
Developing treatments for inborn errors: incentives available to the clinician.Molecular genetics and metabolism, 81 Suppl 1
S. Levitus, T. Boyer, M. Conkright, J. Brien, Cathy Stephens, L. Stathoplos, Daphne Johnson, R. Gelfeld (1998)
US Government Printing Office
A. Clarke (1991)
Non-directive genetic counsellingThe Lancet, 338
N. Holtzman (1977)
Anatomy of a trial.Pediatrics, 60 6
Ja Wilson, G. Jungner (1968)
Principles and practice of screening for disease
P. Pharoah (2001)
Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent DiseaseBMJ : British Medical Journal, 322
N. Holtzman (2003)
Expanding newborn screening: how good is the evidence?JAMA, 290 19
F. Innes (1996)
Why are some people healthy and others not?: The determinants of health of populationsSocial Science & Medicine, 42
R. Faden, A. Chwalow, N. Holtzman, S. Horn (1982)
A survey to evaluate parental consent as public policy for neonatal screening.American journal of public health, 72 12
C. Lawrence (1980)
The role of medicine. Dream, mirage or nemesis?Medical History, 24
R. Lindner (1992)
What drives neonatal screening programs?The New England journal of medicine, 326 7
(2002)
Status and potential of gene therapy in clinical medicine . Assessment of an emerging health technology through systematic survey of clinical gene therapy protocols and published results
S. Stefánsson, H. Jonsson, T. Ingvarsson, I. Manolescu, H. Jónsson, G. Olafsdóttir, E. Pálsdóttir, G. Stefansdóttir, Gudfinna Sveinbjörnsdóttir, M. Frigge, A. Kong, J. Gulcher, K. Stefánsson (2003)
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.American journal of human genetics, 72 6
C. McMurray, J. Tainer (2003)
Cancer, cadmium and genome integrityNature Genetics, 34
H. Hakonarson, E. Halapi (2002)
Genetic analyses in asthma: current concepts and future directions.American journal of pharmacogenomics : genomics-related research in drug development and clinical practice, 2 3
M. Piper, J. Lindenmayer, E. Lengerich, K. Pass, W. Brown, Wendy Crowder, M. Khoury, T. Baker, M. Lloyd-Puryear, J. Bryan (2001)
The Role of State Public Health Agencies in Genetics and Disease Prevention: Results of a National SurveyPublic Health Reports, 116
K. Weiss, J. Terwilliger (2000)
How many diseases does it take to map a gene with SNPs?Nature Genetics, 26
H. Elaine, Hillet, Gretcheni Landenburger, Marvin Natowic (1997)
Public participation in medical policy-making and the status of consumer autonomy: the example of newborn-screening programs in the United States.American journal of public health, 87 8
T. Marteau, Harriet Drake (1995)
Attributions for disability: the influence of genetic screening.Social science & medicine, 40 8
Y. Jin, A. Clark, R. Slebos, Hanan Al-Refai, Jack Taylor, T. Kunkel, M. Resnick, D. Gordenin (2003)
Cadmium is a mutagen that acts by inhibiting mismatch repairNature Genetics, 34
Lynn Smith, J. Byers (2002)
Gene Therapy in the Post-Gelsinger EraJONA's Healthcare Law, Ethics, and Regulation, 4
M. Braekeleer (2001)
Genetics and public health in the 21st century : using genetic information to improve health and prevent diseasePopulation, 56
L. Woolf (1967)
The Dietary Treatment of Phenylketonuria: Not ProvenDevelopmental Medicine & Child Neurology, 9
Lila Guterman (2003)
Choosing eugenics: how far will nations go to eliminate a genetic disease?The Chronicle of higher education, 49 34
S. Feetham (2000)
Comments on the Secretary's Advisory Committee on Genetic Testing document: a public consultation on oversight of genetic tests, January 27, 2000, Baltimore, Maryland.Nursing outlook, 48 3
N. Holtzman (1998)
Eugenics and Genetic TestingScience in Context, 11
O. Bratt (2002)
Hereditary prostate cancer: clinical aspects.The Journal of urology, 168 3
N. Holtzman (2002)
Genetics and social classJournal of Epidemiology and Community Health, 56
J. Hirschhorn, K. Lohmueller, E. Byrne, K. Hirschhorn (2002)
A comprehensive review of genetic association studiesGenetics in Medicine, 4
Some epidemiologists and geneticists claim that integrating genetics into public health policies and programs is necessary and unavoidable. Objective: To examine the extent to which further integration of public health and genetics is warranted. Methods: Synthesis of the literature in four areas: research, genetic services, regulation, and education. The analysis is limited to human genetics. Results: Public support for basic genetic research has and will continue to lead to new applications and to further understanding of human origins and dispersions. Some applied research, particularly for genetic risk factors for common complex diseases, has low yield and is better supported by private funds. The only genetic service for which a public health role is paramount is newborn screening. With the patenting of genes, and the proliferation of commercial interests in genetic tests and directly advertising them to the public, regulation by public health agencies is increasingly important. As most genetic testing and other services will be provided in the personal health care system, education about genetics is best left to the educational and medical systems. Public health practitioners should be aware of the limitations of genetic tests. Conclusions: There is little need for further integration of genetic services and education into public health especially in countries in which public and private health services are dichotomized. Newborn screening and follow-up, however, are most safely and effectively provided under public health auspices. The most important area for strengthening the public health role is in the regulation of genetic tests and other genetic services provided primarily by the private sector. Continued support for basic genetic research is needed.
Public Health Genomics – Karger
Published: Jan 1, 2006
Keywords: Genetics; Newborn screening; Public health; Resource allocation
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.