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/lp/karger/treatment-of-advanced-prostatic-carcinoma-with-cyproterone-acetate-and-DKbJ4MAPn6
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- Publisher
- Karger
- Copyright
- © 1980 S. Karger AG, Basel
- ISSN
- 0302-2838
- eISSN
- 1873-7560
- DOI
- 10.1159/000473313
- Publisher site
- See Article on Publisher Site
Abstract
We report the results from 106 patients with extracapsular (stage C) or widespread (stage D)prostatic cancer, who were treated with cyproterone acetate and orchiectomy and followed for 5 years. Ascontrols we used 40 patients, chosen at random, with stage C and stage D cancer of the prostate gland whowere treated with stilbestrol and orchiectomy. The survival rate is improved in patients treated withcyproterone acetate and orchiectomy compared to the patients treated with stilbestrol and orchiectomy.Treatment with cyproterone seems more effective in those patients with low-stage and low-grade prostaticcancer. The side effects of this therapy are less and milder than those described in estrogenic treatment aloneor with orchiectomy.
Journal
European Urology – Karger
Published: Jan 1, 2017
Keywords: Prostatic cancer; Cyproterone acetate; Stilbestrol; Orchiectomy; Survival