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/lp/karger/psychological-well-being-before-and-after-growth-hormone-treatment-in-iylSODPZI8
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- Publisher
- Karger
- Copyright
- © 1990 S. Karger AG, Basel
- ISSN
- 1663-2818
- eISSN
- 1663-2826
- DOI
- 10.1159/000181584
- Publisher site
- See Article on Publisher Site
Abstract
The effect of recombinant-DNA human growth hormone treatment on psychological well-being and quality of life was studied in adults with GH deficiency (GHD). 24 adults who satisfied strict criteria for GHD took part in a double-blind, placebo-controlled, 6-month trial. Quality of life assessments were performed at entry, 1 and 6 months by means of self-rating questionnaires. This study reports significantly lower scores on quality of life assessment in the GH-deficient patients at entry compared with matched controls, indicating that this population may be psychologically compromised. Preliminary analysis of treatment results shows that after 6 months, those patients receiving active treatment experienced less perceived illness than the placebo group. Significant psychological improvements were noted in the patients’ perception of their energy level and mood.
Journal
Hormone Research in Paediatrics – Karger
Published: Jan 1, 1990
Keywords: Quality of life; Psychological well-being; Growth hormone deficiency