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Potential Sampling Error in Fine Needle Aspiration Biopsy of Dedifferentiated Chondrosarcoma

Potential Sampling Error in Fine Needle Aspiration Biopsy of Dedifferentiated Chondrosarcoma Case Reports Potential Sampling Error in Fine Needle Aspiration Biopsy of Dedifferentiated Chondrosarcoma A Report of 4 Cases Allen C. Rinas, M.S., C.T.(ASCP), C.M.I.A.C., William G. Ward, M.D., and Scott E. Kilpatrick, M.D. Background containing a spindled to polygonal, nonspecific, pleomorphic Dedifferentiated chondrosarcoma is a rare, poorly under- sarcoma unaccompanied by definite matrix material; 1 of stood and often fatal sarcoma that usually manifests as a these had a concomitant core needle biopsy (CNB), also high grade, non–cartilage-producing sarcoma juxtaposed demonstrating pleomorphic sarcoma. The third primary cy- against a low grade chondrosarcoma. A correct diagnosis re- tologic specimen revealed low grade chondrosarcoma, but a quires recognition of both com- concomitant CNB showed only ponents. In the absence of com- a high grade, non–matrix- plete resection, rendering a producing sarcoma. The last Due to sampling error, the specific diagnosis on small patient developed a metastasis diagnosis of dedifferentiated biopsy specimens, such as fine to the opposite femur; FNAB needle aspiration biopsy revealed a high grade spindle chondrosarcoma may be difficult (FNAB), may be extraordi- cell sarcoma. In none of the (if not impossible) to establish by narily difficult. FNAB or CNB specimens were both low and high grade cytologic examination http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

Potential Sampling Error in Fine Needle Aspiration Biopsy of Dedifferentiated Chondrosarcoma

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Publisher
Karger
Copyright
© 2011 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000326205
Publisher site
See Article on Publisher Site

Abstract

Case Reports Potential Sampling Error in Fine Needle Aspiration Biopsy of Dedifferentiated Chondrosarcoma A Report of 4 Cases Allen C. Rinas, M.S., C.T.(ASCP), C.M.I.A.C., William G. Ward, M.D., and Scott E. Kilpatrick, M.D. Background containing a spindled to polygonal, nonspecific, pleomorphic Dedifferentiated chondrosarcoma is a rare, poorly under- sarcoma unaccompanied by definite matrix material; 1 of stood and often fatal sarcoma that usually manifests as a these had a concomitant core needle biopsy (CNB), also high grade, non–cartilage-producing sarcoma juxtaposed demonstrating pleomorphic sarcoma. The third primary cy- against a low grade chondrosarcoma. A correct diagnosis re- tologic specimen revealed low grade chondrosarcoma, but a quires recognition of both com- concomitant CNB showed only ponents. In the absence of com- a high grade, non–matrix- plete resection, rendering a producing sarcoma. The last Due to sampling error, the specific diagnosis on small patient developed a metastasis diagnosis of dedifferentiated biopsy specimens, such as fine to the opposite femur; FNAB needle aspiration biopsy revealed a high grade spindle chondrosarcoma may be difficult (FNAB), may be extraordi- cell sarcoma. In none of the (if not impossible) to establish by narily difficult. FNAB or CNB specimens were both low and high grade cytologic examination

Journal

Acta CytologicaKarger

Published: Jan 1, 2011

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