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To assess the clinical efficacy and safety ofphotoselective vaporization of the prostate (PVP) in thetreatment of patients with acute urinary retention, secondaryto benign prostatic hyperplasia (BPH). Patients andMethods: Thirty-two patients with acute urinary retentiondue to BPH were treated with the green-light laser, in a prospectivetrial. The treatment outcome was evaluated usingthe International Prostate Symptom Score (IPSS), diseasespecificquality of life (QoL) score, postvoiding residualurine volume and maximum urinary flow rate (Q<sub>max</sub>). Followupassessment and sexual function were performed immediatelypostoperatively and at 3, 6 and 12 months. Results:The mean patient age was 72 ± 5 years (range 65-89 years).The mean residual volume presenting with retention was350 ml (range 240-1,200ml). The mean operating time was48.6 ± 5.7 min. The mean catheterization duration after theoperation was 5.6 days (range 3-14 days). The mean IPSSand QoL decreased significantly from 22.5 ± 4.6 and 5.3 ± 1.2to 8.4 ± 5.6 (p = 0.01) and 1.8 ± 1.2 (p = 0.03), respectively.The mean residual volume decreased to 58 ml, the meanQ<sub>max</sub> was 16.2 ± 4.6 ml/s after treatment. Only 2 patients hadrecurrent urinary retention during follow-up. Conclusions: The early clinical results suggest that PVP is a promisingsafe, effective and less-invasive treatment for high-risk patientswith urine retention secondary to BPH.
Current Urology – Karger
Published: Jan 1, 2007
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