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Open-Label Placebos Improve Symptoms in Allergic Rhinitis: A Randomized Controlled Trial

Open-Label Placebos Improve Symptoms in Allergic Rhinitis: A Randomized Controlled Trial It is well known that placebo treatment may have a significant impact on allergic symptoms [1,2,3]. In the traditional view, deception of the patient is crucial for beneficial responses due to placebo treatment [4]. However, a recent study demonstrated intriguing evidence that placebos may work even without concealment in patients with irritable bowel syndrome [5]. This is important because ethical problems related to placebos (e.g. undermining trust in the patient-physician relationship) do not account when using open-label placebos. Here we report a pilot study investigating whether placebos without deception may also work for allergic rhinitis.We conducted a two-group randomized controlled trial including 25 participants with allergic rhinitis. Patients were randomized into two groups. One group received placebos without deception (open-label placebo group), and the other group received no pills (control group). Patient-provider relationship and amount of contact time was held similar for both groups. After 2 weeks we tested whether symptoms and quality of life may have changed due to the open-label placebos. Participants were recruited from fliers in the local university and via social media (mean age 26 ± 9.9 years, 21 women). The study was done in accordance with the Declaration of Helsinki and approved by an http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychotherapy and Psychosomatics Karger

Open-Label Placebos Improve Symptoms in Allergic Rhinitis: A Randomized Controlled Trial

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References (11)

Publisher
Karger
Copyright
© 2016 S. Karger AG, Basel
ISSN
0033-3190
eISSN
1423-0348
DOI
10.1159/000447242
Publisher site
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Abstract

It is well known that placebo treatment may have a significant impact on allergic symptoms [1,2,3]. In the traditional view, deception of the patient is crucial for beneficial responses due to placebo treatment [4]. However, a recent study demonstrated intriguing evidence that placebos may work even without concealment in patients with irritable bowel syndrome [5]. This is important because ethical problems related to placebos (e.g. undermining trust in the patient-physician relationship) do not account when using open-label placebos. Here we report a pilot study investigating whether placebos without deception may also work for allergic rhinitis.We conducted a two-group randomized controlled trial including 25 participants with allergic rhinitis. Patients were randomized into two groups. One group received placebos without deception (open-label placebo group), and the other group received no pills (control group). Patient-provider relationship and amount of contact time was held similar for both groups. After 2 weeks we tested whether symptoms and quality of life may have changed due to the open-label placebos. Participants were recruited from fliers in the local university and via social media (mean age 26 ± 9.9 years, 21 women). The study was done in accordance with the Declaration of Helsinki and approved by an

Journal

Psychotherapy and Psychosomatics – Karger

Published: Jan 1, 2016

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