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Acta Cytologica Nuclear Pseudoinclusions in Angiomyolipoma of the Kidney A Case Report Akiko Sangawa, C.T.(IAC), Masayuki Shintaku, M.D., and Masanori Nishimura, M.D. BACKGROUND: Fine needle biopsy has been utilized is a rather common nuclear feature in angiomyolipoma. for the preoperative diagnosis of angiomyolipoma of the It is presumably one of the manifestations of nuclear kidney. However, the spec- pleomorphism frequently trum of diverse nuclear seen in smooth muscle cells morphology shown by the of angiomyolipoma and Nuclear pseudoinclusions... constituent smooth muscle should not be considered an should not immediately be cells of angiomyolipoma has indication of malignancy. not been fully elucidated. (Acta Cytol 1998;42: regarded as an indication of CASES: An angiomyolipo- 425–429) malignancy in interpreting fine ma was found incidentally in the left kidney of an needle aspiration cytology of Keywords: angiomyoli- asymptomatic, 57-year-old poma, kidney neoplasms, renal tumors. woman, and nephrectomy nuclear pseudoinclusion. was performed. The tumor was composed predominant- Angiomyolipoma is a ly of smooth muscle cells occasionally showing atypical rare, benign mesenchymal tumor of the kidney and nuclear features. Small aggregates of adipocytes were has characteristic ultrasound, angiographic and also found. Direct stamp specimens of the tumor revealed computed tomographic features. The preoperative plump, spindle-shaped
Acta Cytologica – Karger
Published: Jan 1, 2011
Keywords: angiomyolipoma; kidney neoplasms; nuclear pseudoinclusion
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