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Acta Cytologica Laurie Joyce Mango, M.D. The development of the PAPNET Testing System, study procedures were designed to estimate the beginning in 1989, applied a breakthrough technol- percentage of women diagnosed with high grade ogy to automated cervical smear screening. This lesions or cervical carcinoma who could have had semi-automated system was designed for use as a their cervical smear abnormalities identified earlier rescreening device to supplement conventional if PAPNET testing had been used as a supplement microscopy. Through the application of neural net- to conventional screening. work computer technology, the PAPNET system is The results of this multicenter clinical trial pro- able to perform image analysis of the conventional vided an estimate of the percentage of women with cervical smear without the need for any special significant disease who could have had their abnor- preparation techniques. The PAPNET system is de- malities identified earlier (and how much earlier). signed to detect abnormality missed by the conven- The study also provided data for measuring the ef- tional method. The system may effectively increase fect on screening accuracy when PAPNET testing is the accuracy of cervical smear screening by comple- combined with conventional screening as com- menting standard clinical practice.
Acta Cytologica – Karger
Published: Jan 1, 2011
Keywords: image analysis; computer-assisted; cervical smears; mass screening; laboratory diagnosis
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