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Laboratory Implementation and Efficacy Assessment of the ThinPrep Cervical Cancer Screening System

Laboratory Implementation and Efficacy Assessment of the ThinPrep Cervical Cancer Screening System Acta Cytologica Laboratory Implementation and Efficacy Assessment of the ThinPrep Cervical Cancer Screening System David R. Bolick, M.D., F.C.A.P., and Dennis J. Hellman, M.S., S.C.T.(ASCP) OBJECTIVE: To assess the efficacy of a new fluid-based, The ThinPrep Pap Test (TP) (Cytyc Corp., Boxbor- automated, thin-layer system for cervical screening, in ough, Massachusetts, U.S.A.) was approved as a re- routine use in our clinical laboratory. placement for the conventional cervical cytologic STUDY DESIGN: Data from 39,408 conventional cer- smear in May 1996. Though a number of studies vical cytologic smears and have reported increased 10,694 ThinPrep slides col- sensitivity and improved 1,9 lected concurrently were an- These data, from routine clinical specimen adequacy with alyzed to compare diagnostic TP as compared to conven- practice, confirm the increased detection rates, specimen ad- tional smears (CSs), there detection of cervical neoplasia equacy, sensitivity and speci- have been no published ficity. results from a screening when using the TP method. RESULTS: The ThinPrep laboratory in which the slides yielded a significantly ThinPrep Pap Test was higher proportion of low grade squamous intraepithelial implemented for routine use. The efficacy of the CS, lesions (LSILs) and high grade squamous intraepithelial particularly its sensitivity and specimen adequacy, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

Laboratory Implementation and Efficacy Assessment of the ThinPrep Cervical Cancer Screening System

Bolick, David R.; Hellman, Dennis J.
Acta Cytologica , Volume 42 (1): 5 – Jan 1, 2011
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Publisher
Karger
Copyright
© 1998 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000331548
Publisher site
See Article on Publisher Site

Abstract

Acta Cytologica Laboratory Implementation and Efficacy Assessment of the ThinPrep Cervical Cancer Screening System David R. Bolick, M.D., F.C.A.P., and Dennis J. Hellman, M.S., S.C.T.(ASCP) OBJECTIVE: To assess the efficacy of a new fluid-based, The ThinPrep Pap Test (TP) (Cytyc Corp., Boxbor- automated, thin-layer system for cervical screening, in ough, Massachusetts, U.S.A.) was approved as a re- routine use in our clinical laboratory. placement for the conventional cervical cytologic STUDY DESIGN: Data from 39,408 conventional cer- smear in May 1996. Though a number of studies vical cytologic smears and have reported increased 10,694 ThinPrep slides col- sensitivity and improved 1,9 lected concurrently were an- These data, from routine clinical specimen adequacy with alyzed to compare diagnostic TP as compared to conven- practice, confirm the increased detection rates, specimen ad- tional smears (CSs), there detection of cervical neoplasia equacy, sensitivity and speci- have been no published ficity. results from a screening when using the TP method. RESULTS: The ThinPrep laboratory in which the slides yielded a significantly ThinPrep Pap Test was higher proportion of low grade squamous intraepithelial implemented for routine use. The efficacy of the CS, lesions (LSILs) and high grade squamous intraepithelial particularly its sensitivity and specimen adequacy,

Journal

Acta Cytologica – Karger

Published: Jan 1, 2011

Keywords: cervical smears; cervix neoplasms; mass screening; ThinPrep

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